Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

Laura Graña-Suárez; Willem Verboom; Jurriaan Huskens

doi:10.1039/c5cc09074a

Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

Laura Graña-Suárez, Willem Verboom, Jurriaan Huskens

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Abstract

Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.

Original language	English
Pages (from-to)	2597-2600
Number of pages	4
Journal	Chemical communications
Volume	52
Issue number	12
DOIs	https://doi.org/10.1039/c5cc09074a
Publication status	Published - 2016

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2023 OA procedure

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10.1039/c5cc09074a

Supplementary informationFinal published version, 1.05 MBLicence: Taverne
ArticleFinal published version, 1.76 MBLicence: Taverne

Cite this

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title = "Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo",

abstract = "Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.",

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AU - Verboom, Willem

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AB - Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.

KW - 2023 OA procedure

U2 - 10.1039/c5cc09074a

DO - 10.1039/c5cc09074a

M3 - Article

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SP - 2597

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JO - Chemical communications

JF - Chemical communications

IS - 12

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Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

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