Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

Laura Grana Suarez, Willem Verboom, Jurriaan Huskens

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.
Original languageEnglish
Pages (from-to)2597-2600
Number of pages4
JournalChemical communications
Volume52
Issue number12
DOIs
Publication statusPublished - 2016

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Nanoparticles
Coloring Agents
Pharmaceutical Preparations

Keywords

  • METIS-320666
  • IR-103633

Cite this

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Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo. / Grana Suarez, Laura; Verboom, Willem; Huskens, Jurriaan.

In: Chemical communications, Vol. 52, No. 12, 2016, p. 2597-2600.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Verboom, Willem

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AB - Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.

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