Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

Laura Grana Suarez; Willem Verboom; Jurriaan Huskens

doi:10.1039/c5cc09074a

Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

Laura Grana Suarez, Willem Verboom, Jurriaan Huskens

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Scopus)

Abstract

Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.

Original language	English
Pages (from-to)	2597-2600
Number of pages	4
Journal	Chemical communications
Volume	52
Issue number	12
DOIs	https://doi.org/10.1039/c5cc09074a
Publication status	Published - 2016

Keywords

METIS-320666
IR-103633

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10.1039/c5cc09074a

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title = "Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo",

abstract = "Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.",

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T1 - Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

AU - Grana Suarez, Laura

AU - Verboom, Willem

AU - Huskens, Jurriaan

PY - 2016

Y1 - 2016

N2 - Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.

AB - Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.

KW - METIS-320666

KW - IR-103633

U2 - 10.1039/c5cc09074a

DO - 10.1039/c5cc09074a

M3 - Article

VL - 52

SP - 2597

EP - 2600

JO - Chemical communications

JF - Chemical communications

SN - 1359-7345

IS - 12

ER -

Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo

Abstract

Keywords

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