Fluorinated Polyurethane Scaffolds for 19F Magnetic Resonance Imaging

Twan Lammers* (Corresponding Author), Marianne E. Mertens, Philipp Schuster, Khosrow Rahimi, Yang Shi, Volkmar Schulz, Alexander J.C. Kuehne, Stefan Jockenhoevel, Fabian Kiessling (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Researchers used fluorinated polyurethane scaffolds for 19F magnetic resonance imaging. They generated a novel fluorinated polymer based on thermoplastic polyurethane (19F -TPU) which possesses distinct properties rendering it suitable for fluorine-based MRI. The 19F -TPU is synthesized from a perfluorinated aromatic diisocyanate and butanediol. After polymerization, the polyurethane is N-alkylated to obtain a noncrystalline material with partially fluorinated alkyl side chains. To provide proof-of-principle for the usefulness of 19F -TPU for developing MRI-detectable scaffold materials, it was processed into monofilaments via melt spinning.

Original languageEnglish
Pages (from-to)2669-2671
Number of pages3
JournalChemistry of materials
Volume29
Issue number7
DOIs
Publication statusPublished - 11 Apr 2017

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    Lammers, T., Mertens, M. E., Schuster, P., Rahimi, K., Shi, Y., Schulz, V., ... Kiessling, F. (2017). Fluorinated Polyurethane Scaffolds for 19F Magnetic Resonance Imaging. Chemistry of materials, 29(7), 2669-2671. https://doi.org/10.1021/acs.chemmater.6b04649