Fluorinated Polyurethane Scaffolds for 19F Magnetic Resonance Imaging

  • Twan Lammers* (Corresponding Author)
  • , Marianne E. Mertens
  • , Philipp Schuster
  • , Khosrow Rahimi
  • , Yang Shi
  • , Volkmar Schulz
  • , Alexander J.C. Kuehne
  • , Stefan Jockenhoevel
  • , Fabian Kiessling (Corresponding Author)
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
222 Downloads (Pure)

Abstract

Researchers used fluorinated polyurethane scaffolds for 19F magnetic resonance imaging. They generated a novel fluorinated polymer based on thermoplastic polyurethane (19F -TPU) which possesses distinct properties rendering it suitable for fluorine-based MRI. The 19F -TPU is synthesized from a perfluorinated aromatic diisocyanate and butanediol. After polymerization, the polyurethane is N-alkylated to obtain a noncrystalline material with partially fluorinated alkyl side chains. To provide proof-of-principle for the usefulness of 19F -TPU for developing MRI-detectable scaffold materials, it was processed into monofilaments via melt spinning.

Original languageEnglish
Pages (from-to)2669-2671
Number of pages3
JournalChemistry of materials
Volume29
Issue number7
DOIs
Publication statusPublished - 11 Apr 2017

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