From lab-on-a-chip to lab-in-a-cell

Helene Andersson, Albert van den Berg

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    2 Citations (Scopus)

    Abstract

    There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature"s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells. This is followed by a review on the present chip solutions for single cell handling and analysis.
    Original languageUndefined
    Title of host publicationMicrofluidics, BioMEMS, and Medical Microsystems III Progress in Biomedical Optics and Imaging - Proceedings of SPIE
    Place of PublicationBellingham, WA, USA
    PublisherSPIE
    Pages1-12
    Number of pages12
    ISBN (Print)9780819456922
    DOIs
    Publication statusPublished - 2005

    Publication series

    NameBioMEMS for Living Cells
    PublisherSPIE
    Number1
    Volume5718

    Keywords

    • EWI-19859

    Cite this

    Andersson, H., & van den Berg, A. (2005). From lab-on-a-chip to lab-in-a-cell. In Microfluidics, BioMEMS, and Medical Microsystems III Progress in Biomedical Optics and Imaging - Proceedings of SPIE (pp. 1-12). (BioMEMS for Living Cells; Vol. 5718, No. 1). Bellingham, WA, USA: SPIE. https://doi.org/10.1117/12.601553