From LOC to LIC: Using individual cells as experimentation platforms

Helene Andersson; Albert van den Berg

doi:10.1007/s12030-005-0062-4

From LOC to LIC: Using individual cells as experimentation platforms

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells.

Original language	Undefined
Pages (from-to)	319-321
Number of pages	3
Journal	Nanobiotechnology
Volume	1
Issue number	3
DOIs	https://doi.org/10.1007/s12030-005-0062-4
Publication status	Published - 2005

Keywords

EWI-19860

Access to Document

10.1007/s12030-005-0062-4

Cite this

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title = "From LOC to LIC: Using individual cells as experimentation platforms",

abstract = "There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature{\textquoteright}s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells.",

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author = "Helene Andersson and {van den Berg}, Albert",

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AU - Andersson, Helene

AU - van den Berg, Albert

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N2 - There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells.

AB - There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells.

KW - EWI-19860

U2 - 10.1007/s12030-005-0062-4

DO - 10.1007/s12030-005-0062-4

M3 - Article

SN - 1551-1286

VL - 1

SP - 319

EP - 321

JO - Nanobiotechnology

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