From Nano to Macro: Multiscale Materials for Improved Stem Cell Culturing and Analysis

Jeroen Christianus Hermanus Leijten; A. Khademhosseini

doi:10.1016/j.stem.2015.12.013

From Nano to Macro: Multiscale Materials for Improved Stem Cell Culturing and Analysis

Jeroen Christianus Hermanus Leijten, A. Khademhosseini

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Abstract

Stem cells respond to nanoscale, microscale, and macroscale cues, such as matrix, growth factors, and niche organization, which are difficult to physiologically recapitulate in culture. We discuss how utilizing bioengineering approaches to manipulate and integrate spatiotemporal cues across these discrete length scales can improve traditional methods for controlling cell fate.

Original language	English
Pages (from-to)	20-24
Journal	Cell stem cell
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2015.12.013
Publication status	Published - 7 Jan 2016

Keywords

IR-103550
METIS-321590

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10.1016/j.stem.2015.12.013

P__TNW_DBE_Group_Accepted Papers_2016 Accepted Papers_In METIS ingevoerd_Website_Leijten - 2016 - 1st From Nano to Macro Multiscale Materials for Improved Stem Cell Culturing and AnalysisFinal published version, 1.26 MB

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abstract = "Stem cells respond to nanoscale, microscale, and macroscale cues, such as matrix, growth factors, and niche organization, which are difficult to physiologically recapitulate in culture. We discuss how utilizing bioengineering approaches to manipulate and integrate spatiotemporal cues across these discrete length scales can improve traditional methods for controlling cell fate.",

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AB - Stem cells respond to nanoscale, microscale, and macroscale cues, such as matrix, growth factors, and niche organization, which are difficult to physiologically recapitulate in culture. We discuss how utilizing bioengineering approaches to manipulate and integrate spatiotemporal cues across these discrete length scales can improve traditional methods for controlling cell fate.

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KW - METIS-321590

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DO - 10.1016/j.stem.2015.12.013

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From Nano to Macro: Multiscale Materials for Improved Stem Cell Culturing and Analysis

Abstract

Keywords

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