Functionality of epidermal melanin pigments: knowledge on UV-dissipative mechanisms and research perspectives

Annemarie Huijser; Alessandro Pezzella; Villy Sundström

doi:10.1039/c1cp20131j

Functionality of epidermal melanin pigments: knowledge on UV-dissipative mechanisms and research perspectives

Annemarie Huijser, Alessandro Pezzella, Villy Sundström

Research output: Contribution to journal › Article › Academic › peer-review

80 Citations (Scopus)

Abstract

So far it is not known whether epidermal melanins are solely photoprotective or also phototoxic. Also largely unknown are underlying UV-induced mechanisms and impact of the chemical structure. This perspective will focus on the current insights into the UV-dissipative mechanisms in melanin model systems and the implications for the in vivo pigments. We will also identify future research perspectives towards a full understanding of the functionality of epidermal pigments.

Original language	English
Pages (from-to)	9119-9127
Journal	Physical chemistry chemical physics
Volume	13
Issue number	20
DOIs	https://doi.org/10.1039/c1cp20131j
Publication status	Published - 2011
Externally published	Yes

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title = "Functionality of epidermal melanin pigments: knowledge on UV-dissipative mechanisms and research perspectives",

abstract = "So far it is not known whether epidermal melanins are solely photoprotective or also phototoxic. Also largely unknown are underlying UV-induced mechanisms and impact of the chemical structure. This perspective will focus on the current insights into the UV-dissipative mechanisms in melanin model systems and the implications for the in vivo pigments. We will also identify future research perspectives towards a full understanding of the functionality of epidermal pigments.",

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AU - Pezzella, Alessandro

AU - Sundström, Villy

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AB - So far it is not known whether epidermal melanins are solely photoprotective or also phototoxic. Also largely unknown are underlying UV-induced mechanisms and impact of the chemical structure. This perspective will focus on the current insights into the UV-dissipative mechanisms in melanin model systems and the implications for the in vivo pigments. We will also identify future research perspectives towards a full understanding of the functionality of epidermal pigments.

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JO - Physical chemistry chemical physics

JF - Physical chemistry chemical physics

IS - 20

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Functionality of epidermal melanin pigments: knowledge on UV-dissipative mechanisms and research perspectives

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