Functionalizing the glycocalyx of living cells with supramolecular guest ligands for cucurbit[8]uril-mediated assembly

E. Cavatorta, Mark Lloyd Verheijden, W.P.E. van Roosmalen, Jens Voskuhl, Jurriaan Huskens, Pascal Jonkheijm

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Abstract

Multiple naphthol ligands were installed on the glycocalyx of white blood cells via metabolic labeling and subsequent strain promoted azide–alkyne cycloaddition. Only when cucurbit[8]uril was present to drive the formation of ternary complexes, cells specifically assembled on a methylviologen functionalized supported lipid bilayer through multivalent interactions
Original languageEnglish
Pages (from-to)7146-7149
Number of pages4
JournalChemical communications
Volume52
Issue number44
DOIs
Publication statusPublished - 2016

Keywords

  • IR-103523
  • METIS-320644

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