Functionalizing the glycocalyx of living cells with supramolecular guest ligands for cucurbit[8]uril-mediated assembly

Emanuela Cavatorta; Mark L. Verheijden; Wies van Roosmalen; Jens Voskuhl; Jurriaan Huskens; Pascal Jonkheijm

doi:10.1039/C6cc01693F

Functionalizing the glycocalyx of living cells with supramolecular guest ligands for cucurbit[8]uril-mediated assembly

Emanuela Cavatorta, Mark L. Verheijden, Wies van Roosmalen, Jens Voskuhl, Jurriaan Huskens^*, Pascal Jonkheijm^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Multiple naphthol ligands were installed on the glycocalyx of white blood cells via metabolic labeling and subsequent strain promoted azide–alkyne cycloaddition. Only when cucurbit[8]uril was present to drive the formation of ternary complexes, cells specifically assembled on a methylviologen functionalized supported lipid bilayer through multivalent interactions

Original language	English
Pages (from-to)	7146-7149
Number of pages	4
Journal	Chemical communications
Volume	52
Issue number	44
DOIs	https://doi.org/10.1039/C6cc01693F
Publication status	Published - 2016

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2023 OA procedure

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10.1039/C6cc01693F

ArticleFinal published version, 1.85 MBLicence: Taverne
Supporting InformationFinal published version, 874 KBLicence: Taverne

Cite this

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title = "Functionalizing the glycocalyx of living cells with supramolecular guest ligands for cucurbit[8]uril-mediated assembly",

abstract = "Multiple naphthol ligands were installed on the glycocalyx of white blood cells via metabolic labeling and subsequent strain promoted azide–alkyne cycloaddition. Only when cucurbit[8]uril was present to drive the formation of ternary complexes, cells specifically assembled on a methylviologen functionalized supported lipid bilayer through multivalent interactions",

keywords = "2023 OA procedure",

author = "Emanuela Cavatorta and Verheijden, \{Mark L.\} and \{van Roosmalen\}, Wies and Jens Voskuhl and Jurriaan Huskens and Pascal Jonkheijm",

year = "2016",

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journal = "Chemical communications",

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AU - Cavatorta, Emanuela

AU - Verheijden, Mark L.

AU - van Roosmalen, Wies

AU - Voskuhl, Jens

AU - Huskens, Jurriaan

AU - Jonkheijm, Pascal

PY - 2016

Y1 - 2016

N2 - Multiple naphthol ligands were installed on the glycocalyx of white blood cells via metabolic labeling and subsequent strain promoted azide–alkyne cycloaddition. Only when cucurbit[8]uril was present to drive the formation of ternary complexes, cells specifically assembled on a methylviologen functionalized supported lipid bilayer through multivalent interactions

AB - Multiple naphthol ligands were installed on the glycocalyx of white blood cells via metabolic labeling and subsequent strain promoted azide–alkyne cycloaddition. Only when cucurbit[8]uril was present to drive the formation of ternary complexes, cells specifically assembled on a methylviologen functionalized supported lipid bilayer through multivalent interactions

KW - 2023 OA procedure

U2 - 10.1039/C6cc01693F

DO - 10.1039/C6cc01693F

M3 - Article

SN - 1359-7345

VL - 52

SP - 7146

EP - 7149

JO - Chemical communications

JF - Chemical communications

IS - 44

ER -

Functionalizing the glycocalyx of living cells with supramolecular guest ligands for cucurbit[8]uril-mediated assembly

Abstract

Keywords

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