Geometry based dynamic modeling of the neuron-electrode interface

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    2 Citations (Scopus)
    56 Downloads (Pure)

    Abstract

    A dynamic model of the neuron-electrode interface is presented which is based on the interface geometry and the electrical properties of the neuronal membrane. The model is used to compute the potential at the electrode and the local membrane potentials. Extracellular as well as intracellular current stimulation can be simulated. The results demonstrate that extracellular recorded action potentials with several shapes and amplitudes can be produced, depending on the properties of the interface and the membrane. With homogeneous membrane properties, only small amplitudes are simulated, High amplitudes are produced with decreased concentration of voltage sensitive channels in the lower membrane. Resemblance of the shape of the intracellular potential is accomplished by decreasing the capacity of the lower membrane
    Original languageUndefined
    Title of host publicationProc. of 2000 World Congress on Medical Physics and Biomedical Engineering
    Place of PublicationChicago, USA
    PublisherIEEE
    Pages-
    Number of pages4
    ISBN (Print)0-7803-6468-6 C
    DOIs
    Publication statusPublished - 23 Jul 2000
    Event22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2000 - Chicago, United States
    Duration: 23 Jul 200028 Jul 2000
    Conference number: 22

    Publication series

    Name
    PublisherIEEE
    Volume3

    Conference

    Conference22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2000
    Abbreviated titleEMBC
    CountryUnited States
    CityChicago
    Period23/07/0028/07/00

    Keywords

    • METIS-114030
    • IR-17138

    Cite this