Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator

C.G.J. Koopal; M.C. Feiters; R.J.M. Nolte; B. de Ruiter; R.B.M. Schasfoort

doi:10.1016/0956-5663(92)80003-T

Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator

C.G.J. Koopal, M.C. Feiters, R.J.M. Nolte^*, B. de Ruiter, R.B.M. Schasfoort

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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28 Downloads (Pure)

Abstract

Template synthesis inside track-etch membranes is employed to create conducting microtubules of polypyrrole. Within these tubules, glucose oxidase can be adsorbed irreversibly, while retaining its catalytic activity. A glucose sensor is described utilizing the polypyrrole microtubules as mediator. With this sensor glucose can be measured amperometrically in the concentration range 1-30 mM. The sensor is highly selective with respect to other substrates and the sensor response is independent of oxygen concentration. Evidence is presented that in the biosensor direct electron transfer may occur between glucose oxidase and the polypyrrole.

Original language	English
Pages (from-to)	461-471
Number of pages	11
Journal	Biosensors and bioelectronics
Volume	7
Issue number	7
DOIs	https://doi.org/10.1016/0956-5663(92)80003-T
Publication status	Published - 1 Jan 1992
Externally published	Yes

Keywords

Amperometry
Conducting polymers
Direct electron transfer
Glucose sensors
Microtubules

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10.1016/0956-5663(92)80003-T

Koopal1992glucoseFinal published version, 1.59 MB

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title = "Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator",

abstract = "Template synthesis inside track-etch membranes is employed to create conducting microtubules of polypyrrole. Within these tubules, glucose oxidase can be adsorbed irreversibly, while retaining its catalytic activity. A glucose sensor is described utilizing the polypyrrole microtubules as mediator. With this sensor glucose can be measured amperometrically in the concentration range 1-30 mM. The sensor is highly selective with respect to other substrates and the sensor response is independent of oxygen concentration. Evidence is presented that in the biosensor direct electron transfer may occur between glucose oxidase and the polypyrrole.",

keywords = "Amperometry, Conducting polymers, Direct electron transfer, Glucose sensors, Microtubules",

author = "C.G.J. Koopal and M.C. Feiters and R.J.M. Nolte and {de Ruiter}, B. and R.B.M. Schasfoort",

year = "1992",

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T1 - Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator

AU - Koopal, C.G.J.

AU - Feiters, M.C.

AU - Nolte, R.J.M.

AU - de Ruiter, B.

AU - Schasfoort, R.B.M.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Template synthesis inside track-etch membranes is employed to create conducting microtubules of polypyrrole. Within these tubules, glucose oxidase can be adsorbed irreversibly, while retaining its catalytic activity. A glucose sensor is described utilizing the polypyrrole microtubules as mediator. With this sensor glucose can be measured amperometrically in the concentration range 1-30 mM. The sensor is highly selective with respect to other substrates and the sensor response is independent of oxygen concentration. Evidence is presented that in the biosensor direct electron transfer may occur between glucose oxidase and the polypyrrole.

AB - Template synthesis inside track-etch membranes is employed to create conducting microtubules of polypyrrole. Within these tubules, glucose oxidase can be adsorbed irreversibly, while retaining its catalytic activity. A glucose sensor is described utilizing the polypyrrole microtubules as mediator. With this sensor glucose can be measured amperometrically in the concentration range 1-30 mM. The sensor is highly selective with respect to other substrates and the sensor response is independent of oxygen concentration. Evidence is presented that in the biosensor direct electron transfer may occur between glucose oxidase and the polypyrrole.

KW - Amperometry

KW - Conducting polymers

KW - Direct electron transfer

KW - Glucose sensors

KW - Microtubules

U2 - 10.1016/0956-5663(92)80003-T

DO - 10.1016/0956-5663(92)80003-T

M3 - Article

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VL - 7

SP - 461

EP - 471

JO - Biosensors and bioelectronics

JF - Biosensors and bioelectronics

SN - 0956-5663

IS - 7

ER -