Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator

C.G.J. Koopal, M.C. Feiters, R.J.M. Nolte, B. de Ruiter, R.B.M. Schasfoort

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Abstract

Template synthesis inside track-etch membranes is employed to create conducting microtubules of polypyrrole. Within these tubules, glucose oxidase can be adsorbed irreversibly, while retaining its catalytic activity. A glucose sensor is described utilizing the polypyrrole microtubules as mediator. With this sensor glucose can be measured amperometrically in the concentration range 1-30 mM. The sensor is highly selective with respect to other substrates and the sensor response is independent of oxygen concentration. Evidence is presented that in the biosensor direct electron transfer may occur between glucose oxidase and the polypyrrole.

Original languageEnglish
Pages (from-to)461-471
Number of pages11
JournalBiosensors and bioelectronics
Volume7
Issue number7
DOIs
Publication statusPublished - 1 Jan 1992
Externally publishedYes

Fingerprint

Glucose sensors
Polypyrroles
Glucose Oxidase
Glucose oxidase
Membranes
Glucose
Microtubules
Sensors
Biosensing Techniques
Biosensors
Catalyst activity
Electrons
Oxygen
Substrates
polypyrrole

Keywords

  • Amperometry
  • Conducting polymers
  • Direct electron transfer
  • Glucose sensors
  • Microtubules

Cite this

Koopal, C.G.J. ; Feiters, M.C. ; Nolte, R.J.M. ; de Ruiter, B. ; Schasfoort, R.B.M. / Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator. In: Biosensors and bioelectronics. 1992 ; Vol. 7, No. 7. pp. 461-471.
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Glucose sensor utilizing polypyrrole incorporated in tract-etch membranes as the mediator. / Koopal, C.G.J.; Feiters, M.C.; Nolte, R.J.M.; de Ruiter, B.; Schasfoort, R.B.M.

In: Biosensors and bioelectronics, Vol. 7, No. 7, 01.01.1992, p. 461-471.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Koopal, C.G.J.

AU - Feiters, M.C.

AU - Nolte, R.J.M.

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AU - Schasfoort, R.B.M.

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KW - Direct electron transfer

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