Guest encapsulation in a water-soluble molecular capsule based on ionic interactions

F. Corbellini, Luigi Di Costanzo, Mercedes Crego Calama, Silvano Geremia, David Reinhoudt

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    150 Citations (Scopus)


    We report on the synthesis and characterization of a water-soluble molecular capsule based on multiple ionic interactions. The assembly has been studied by means of 1H NMR, ESI-MS spectroscopy, and isothermal titration calorimetry (ITC), showing an association constant in water, Ka, of 3.3 × 104 M-1. The achieved water solubility of the system opens the possibility of using this supramolecular assembly for molecular recognition in pure water. Encapsulation studies have been performed and are reported in this Communication
    Original languageUndefined
    Pages (from-to)9946-9947
    Number of pages2
    JournalJournal of the American Chemical Society
    Issue number33
    Publication statusPublished - 2003


    • METIS-215672
    • IR-40884

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