Abstract
The inner walls of a glass microreactor were functionalized in a one-step procedure with a single layer of a strong perfluoroalkylsulfonic acid. The applicability of the catalytic device was demonstrated in the successful hydrolysis of benzaldehyde dimethyl acetal in acetonitrile, achieving quantitative conversion within a residence time of only 60 s. Furthermore, the catalytic system showed high conversion for the Friedlander quinoline synthesis between 2-aminobenzophenone and ethyl acetoacetate. The cyclization of pseudoionone in methylcyclohexane proved the wide applicability of the acid-functionalized microreactor also for reactions carried out in apolar media. The platform showed activity for 6 h to 2 days, depending on the solvent, and was reactivated by simple treatment with the catalyst precursor.
Original language | Undefined |
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Pages (from-to) | 127-131 |
Number of pages | 4 |
Journal | Journal of flow chemistry |
Volume | 3 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2013 |
Keywords
- METIS-301554
- IR-90116