High flow rate microsieve for bio medical applications

C.J.M. van Rijn, W. Nijdam, Michael Curt Elwenspoek

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    A new composite filtration membrane having a thin filtration or sieving layer has been developed. This filtration membrane with a high pore density and a narrow pore size distribution on a macro porous support shows good separation behaviour and a high flow rate. Because of the construction method, the openings are no longer restricted to circular shapes, but can be chosen freely. In this case a microsieve with slits will be presented. The main advantage of a slit over a circular opening is the higher flow rate. In this paper a process description for manufacturing is presented and the flow rate behaviour of the membrane with slits will be compared with a membrane with circular perforations. Also results of experiments of leukocyte removal from erythrocyte concentrates with a silicon microsieve will be discussed.
    Original languageEnglish
    Pages (from-to)995-1000
    Number of pages6
    JournalJournal of dynamic systems, measurement and control : transactions of the ASME
    Publication statusPublished - 1995


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