High-sensitivity frequency modulation CARS with a compact and fast tunable fiber-based light source

Thomas Wurthwein; Maximilian Brinkmann; Tim Hellwig; Kristin Wallmeier; Carsten Fallnich

doi:10.1364/OL.425578

High-sensitivity frequency modulation CARS with a compact and fast tunable fiber-based light source

Thomas Wurthwein^*, Maximilian Brinkmann, Tim Hellwig, Kristin Wallmeier, Carsten Fallnich

^*Corresponding author for this work

Laser Physics & Nonlinear Optics

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Abstract

Frequency modulation (FM) coherent anti-Stokes Raman scattering (CARS) is presented, using a compact as well as fast and widely tunable fiber-based light source. With this light source, Raman resonances between 700 cm-1 and 3200 cm-1 can be addressed via wavelength tuning within only 5 ms, which allows forFMCARS measurements with frame-to-frame wavelength switching. Moreover, the functionality for high-sensitivity FM CARS measurements was integrated by means of fiber optics to keep a stable and reliable operation. The light source accomplishedFMCARS measurements with a 40 times enhanced sensitivity at a lock-in amplifier (LIA) bandwidth of 1 Hz. For fast imaging with frame-to-frame wavelength switching at a LIA bandwidth of 1 MHz, an 18-fold contrast enhancement could be verified, making this light source ideal for routine and out-of-lab FM CARSmeasurements for medical diagnostics or environmental sensing.

Original language	English
Pages (from-to)	3544-3547
Number of pages	4
Journal	Optics letters
Volume	46
Issue number	15
Early online date	21 Jul 2021
DOIs	https://doi.org/10.1364/OL.425578
Publication status	Published - 1 Aug 2021

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n/a OA procedure

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10.1364/OL.425578

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abstract = "Frequency modulation (FM) coherent anti-Stokes Raman scattering (CARS) is presented, using a compact as well as fast and widely tunable fiber-based light source. With this light source, Raman resonances between 700 cm-1 and 3200 cm-1 can be addressed via wavelength tuning within only 5 ms, which allows forFMCARS measurements with frame-to-frame wavelength switching. Moreover, the functionality for high-sensitivity FM CARS measurements was integrated by means of fiber optics to keep a stable and reliable operation. The light source accomplishedFMCARS measurements with a 40 times enhanced sensitivity at a lock-in amplifier (LIA) bandwidth of 1 Hz. For fast imaging with frame-to-frame wavelength switching at a LIA bandwidth of 1 MHz, an 18-fold contrast enhancement could be verified, making this light source ideal for routine and out-of-lab FM CARSmeasurements for medical diagnostics or environmental sensing.",

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AU - Wurthwein, Thomas

AU - Brinkmann, Maximilian

AU - Hellwig, Tim

AU - Wallmeier, Kristin

AU - Fallnich, Carsten

PY - 2021/8/1

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N2 - Frequency modulation (FM) coherent anti-Stokes Raman scattering (CARS) is presented, using a compact as well as fast and widely tunable fiber-based light source. With this light source, Raman resonances between 700 cm-1 and 3200 cm-1 can be addressed via wavelength tuning within only 5 ms, which allows forFMCARS measurements with frame-to-frame wavelength switching. Moreover, the functionality for high-sensitivity FM CARS measurements was integrated by means of fiber optics to keep a stable and reliable operation. The light source accomplishedFMCARS measurements with a 40 times enhanced sensitivity at a lock-in amplifier (LIA) bandwidth of 1 Hz. For fast imaging with frame-to-frame wavelength switching at a LIA bandwidth of 1 MHz, an 18-fold contrast enhancement could be verified, making this light source ideal for routine and out-of-lab FM CARSmeasurements for medical diagnostics or environmental sensing.

AB - Frequency modulation (FM) coherent anti-Stokes Raman scattering (CARS) is presented, using a compact as well as fast and widely tunable fiber-based light source. With this light source, Raman resonances between 700 cm-1 and 3200 cm-1 can be addressed via wavelength tuning within only 5 ms, which allows forFMCARS measurements with frame-to-frame wavelength switching. Moreover, the functionality for high-sensitivity FM CARS measurements was integrated by means of fiber optics to keep a stable and reliable operation. The light source accomplishedFMCARS measurements with a 40 times enhanced sensitivity at a lock-in amplifier (LIA) bandwidth of 1 Hz. For fast imaging with frame-to-frame wavelength switching at a LIA bandwidth of 1 MHz, an 18-fold contrast enhancement could be verified, making this light source ideal for routine and out-of-lab FM CARSmeasurements for medical diagnostics or environmental sensing.

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High-sensitivity frequency modulation CARS with a compact and fast tunable fiber-based light source

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