High signal to noise ratio in low field nmr on chip, simulations and experimental results

H. Wensink, D.C. Hermes, Albert van den Berg

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    27 Citations (Scopus)
    319 Downloads (Pure)

    Abstract

    A /spl mu/fluidic chip with integrated microcoil was developed for nuclear magnetic resonance (NMR) spectroscopy on limited volume samples (nanoliters range). This chip will be used for the online monitoring of micro chemical reactions. Design rules for the microcoil to achieve the best signal to noise ratio (SNR) were obtained by finite element simulation. For pure water in a low field NMR magnet (60 MHz., i.e. 1.4 Tesla) a SNR of 550 was achieved which is to our knowledge higher than any other /spl mu/fluidic chip with integrated detection coil. It is also shown that a spectral resolution of 0.025 ppm is obtained when a microchannel with an arbitrary cross section is placed parallel to the magnetic field. A high SNR at low magnetic field for small volume samples is essential for the development of portable NMR systems where mini permanent magnets of 1 Tesla are used
    Original languageUndefined
    Title of host publicationMicro Electro Mechanical Systems, 2004. 17th IEEE International Conference on. (MEMS)
    Place of PublicationPiscataway
    PublisherIEEE
    Pages407-410
    Number of pages4
    ISBN (Print)0-7803-8265-x
    DOIs
    Publication statusPublished - 2004
    Event17th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2004 - Maastricht, Netherlands
    Duration: 25 Jan 200429 Jan 2004
    Conference number: 17

    Publication series

    NameMicro Electro Mechanical Systems, 2004
    PublisherIEEE Computer Society
    Volume04CH37517

    Conference

    Conference17th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2004
    Abbreviated titleMEMS
    Country/TerritoryNetherlands
    CityMaastricht
    Period25/01/0429/01/04

    Keywords

    • IR-47331
    • EWI-10744
    • METIS-217676

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