Abstract
High throughput biomaterials screening largely remains unexplored. The present study was an attempt to explore the area of high throughput as well as high content screening of cell surface topographic interaction. An array of surface topographies called TopoChip was fabricated using a widely used polymer in tissue engineering, Poly (DL-lactic acid). The topographies were subsequently screened for their mitogenic effect on cells. We were able to detect topographic parameters responsible for mitogenic effect of surface topographies.
Original language | English |
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Title of host publication | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 |
Editors | Sabeth Verpoorte, Helen Andersson-Svahn, Jenny Emnéus, Nicole Pamme |
Place of Publication | San Diego |
Publisher | The Chemical and Biological Microsystems Society |
Pages | 2083-2084 |
Number of pages | 3 |
ISBN (Electronic) | 978-0-9798064-3-8 |
ISBN (Print) | 978-1-6183906-2-2 |
Publication status | Published - 3 Oct 2010 |
Event | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14 |
Publication series
Name | International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings] |
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Publisher | The Chemical and Biological Microsystems Society |
Volume | 2010 |
ISSN (Print) | 1556-5904 |
Conference
Conference | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 |
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Abbreviated title | MicroTAS 2010 |
Country/Territory | Netherlands |
City | Groningen |
Period | 3/10/10 → 7/10/10 |
Keywords
- Biomaterials
- High-throughput screening
- Micro-nanotopographies
- Cell behavior