Highly non-linear contrast agent oscillations: The compression-only behavior

S.M. van der Meer; P.G. Marmottant; S. Hilgenfeldt; M. Versluis; D. Lohse; C.T. Chin; A. Bouakaz; F. Mastik; M. Emmer; N. de Jong

doi:10.1109/ULTSYM.2005.1603012

Highly non-linear contrast agent oscillations: The compression-only behavior

S.M. van der Meer^*
, P.G. Marmottant
, S. Hilgenfeldt
, M. Versluis
, D. Lohse
, C.T. Chin
, A. Bouakaz
, F. Mastik
, M. Emmer
, N. de Jong

^*Corresponding author for this work

Physics of Fluids

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

3 Citations (Scopus)

3 Downloads (Pure)

Abstract

Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

Original language	English
Title of host publication	2005 IEEE Ultrasonics Symposium
Pages	974-976
Number of pages	3
Volume	2
DOIs	https://doi.org/10.1109/ULTSYM.2005.1603012
Publication status	Published - 1 Dec 2005
Event	IEEE Ultrasonics Symposium 2005 - Rotterdam, Netherlands Duration: 18 Sept 2005 → 21 Sept 2005

Conference

Conference	IEEE Ultrasonics Symposium 2005
Country/Territory	Netherlands
City	Rotterdam
Period	18/09/05 → 21/09/05

Keywords

Buckling model
Compression-only
Contrast agents

Access to Document

10.1109/ULTSYM.2005.1603012

Cite this

@inproceedings{0ddce23cbac5453ab8d52cf46818aa4f,

title = "Highly non-linear contrast agent oscillations: The compression-only behavior",

abstract = "Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33\% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.",

keywords = "Buckling model, Compression-only, Contrast agents",

author = "\{van der Meer\}, S.M. and P.G. Marmottant and S. Hilgenfeldt and M. Versluis and D. Lohse and C.T. Chin and A. Bouakaz and F. Mastik and M. Emmer and \{de Jong\}, N.",

year = "2005",

month = dec,

day = "1",

doi = "10.1109/ULTSYM.2005.1603012",

language = "English",

isbn = "9780780393820",

volume = "2",

pages = "974--976",

booktitle = "2005 IEEE Ultrasonics Symposium",

note = "IEEE Ultrasonics Symposium 2005 ; Conference date: 18-09-2005 Through 21-09-2005",

}

van der Meer, SM, Marmottant, PG, Hilgenfeldt, S, Versluis, M , Lohse, D, Chin, CT, Bouakaz, A, Mastik, F, Emmer, M & de Jong, N 2005, Highly non-linear contrast agent oscillations: The compression-only behavior. in 2005 IEEE Ultrasonics Symposium. vol. 2, 1603012, pp. 974-976, IEEE Ultrasonics Symposium 2005, Rotterdam, Netherlands, 18/09/05. https://doi.org/10.1109/ULTSYM.2005.1603012

TY - GEN

T1 - Highly non-linear contrast agent oscillations

T2 - IEEE Ultrasonics Symposium 2005

AU - van der Meer, S.M.

AU - Marmottant, P.G.

AU - Hilgenfeldt, S.

AU - Versluis, M.

AU - Lohse, D.

AU - Chin, C.T.

AU - Bouakaz, A.

AU - Mastik, F.

AU - Emmer, M.

AU - de Jong, N.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

AB - Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

KW - Buckling model

KW - Compression-only

KW - Contrast agents

UR - https://www.scopus.com/pages/publications/33847107587

U2 - 10.1109/ULTSYM.2005.1603012

DO - 10.1109/ULTSYM.2005.1603012

M3 - Conference contribution

AN - SCOPUS:33847107587

SN - 9780780393820

VL - 2

SP - 974

EP - 976

BT - 2005 IEEE Ultrasonics Symposium

Y2 - 18 September 2005 through 21 September 2005

ER -

Highly non-linear contrast agent oscillations: The compression-only behavior

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Keywords

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