Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM

Brett W. Sperry*, Timothy M. Bateman, Esma A. Akin, Paco E. Bravo, Wengen Chen, Vasken Dilsizian, Fabien Hyafil, Yiu Ming Khor, Robert J.H. Miller, Riemer H.J.A. Slart, Piotr Slomka, Hein Verberne, Edward J. Miller, Chi Liu*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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This information statement from the Society of Nuclear Medicine and Molecular Imaging, American Society of Nuclear Cardiology, and European Association of Nuclear Medicine describes the performance, interpretation, and reporting of hot spot imaging in nuclear cardiology. The field of nuclear cardiology has historically focused on cold spot imaging for the interpretation of myocardial ischemia and infarction. Hot spot imaging has been an important part of nuclear medicine, particularly for oncology or infection indications, and the use of hot spot imaging in nuclear cardiology continues to expand. This document focuses on image acquisition and processing, methods of quantification, indications, protocols, and reporting of hot spot imaging. Indications discussed include myocardial viability, myocardial inflammation, device or valve infection, large vessel vasculitis, valve calcification and vulnerable plaques, and cardiac amyloidosis. This document contextualizes the foundations of image quantification and highlights reporting in each indication for the cardiac nuclear imager.

Original languageEnglish
Pages (from-to)626-652
Number of pages27
JournalJournal of nuclear cardiology
Issue number2
Publication statusPublished - Apr 2023


  • Basic science
  • diseases/processes
  • modalities
  • NLA


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