Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds

Mithun Kuniyil Ajith Singh, Vinay Parameshwarappa, Ellen Hendriksen, Wiendelt Steenbergen, Srirang Manohar

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)
76 Downloads (Pure)

Abstract

Reflection artifacts caused by the high signal from the optical fiber/ needle tip reflecting off the seed is an important problem in minimally invasive photoacoustic imaging of brachytherapy seeds. The presence of these artifacts confounds the interpretation of images and reduces contrast. We apply a new method called PAFUSion (Photoacoustic-guided focused ultrasound) to identify and reduce reflection artifacts generated in interstitial illumination imaging of brachytherapy seeds. We present the system comprising of a US imager and linear array, with illumination provided via a cutting needle. Non-radioactive brachytherapy seeds are implanted in a tissue mimicking phantom and ex vivo porcine tissue. The PAFUSion-corrected imaging results successfully demonstrate that our approach can identify and strongly reduce reflection artifacts in the context of photoacoustic needle. The phantom result also shows that multi-spectral photoacoustics can separate signals between the seeds and other optical absorbers.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound: Imaging and Sensing 2017
PublisherSPIE
Volume10064
ISBN (Electronic)9781510605695
DOIs
Publication statusPublished - 2017
EventPhotons Plus Ultrasound: Imaging and Sensing 2017 - San Francisco, United States
Duration: 29 Jan 20171 Feb 2017

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2017
CountryUnited States
CitySan Francisco
Period29/01/171/02/17

Keywords

  • Brachytherapy
  • Photoacoustic needle
  • Photoacoustic-guided focused ultrasound
  • Photoacoustics
  • Reflection artifacts
  • Ultrasound

Fingerprint Dive into the research topics of 'Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds'. Together they form a unique fingerprint.

Cite this