The positron emitters 18F, 68Ga, 124I, and 89Zr are all relevant in small-animal PET. Each of these radionuclides has different positron energies and ranges and a different fraction of single photons emitted. Average positron ranges larger than the intrinsic spatial resolution of the scanner (for 124I and 68Ga) will deteriorate the effective spatial resolution and activity recovery coefficient (RC) for small lesions or phantom structures. The presence of single photons (for 124I and 89Zr) could increase image noise and spillover ratios (SORs).
- Nuclear medicine
- PET scanner
- Image quality
Disselhorst, J. A., Brom, M., Laverman, P., Slump, C. H., Boerman, O. C., Oyen, W. J. G., ... Visser, E. P. (2010). Image-quality assessment for several positron emitters using the nema nu 4-2009 standards in the siemens inveon small-animal pet scanner. Journal of nuclear medicine, 51(4), 610-617. https://doi.org/10.2967/jnumed.109.068858