Imaging of Small Vessels Using Photoacoustics: An In Vivo Study

Ronald I. Siphanto; R.G.M. Kolkman; A. Huisjes; M.H. Pilatou; F.F.M. de Mul; Wiendelt Steenbergen; Leon N.A. van Adrichem

doi:10.1002/lsm.20100

Imaging of Small Vessels Using Photoacoustics: An In Vivo Study

Ronald I. Siphanto, R.G.M. Kolkman, A. Huisjes, M.H. Pilatou, F.F.M. de Mul, Wiendelt Steenbergen, Leon N.A. van Adrichem

Research output: Contribution to journal › Article › Academic › peer-review

15 Citations (Scopus)

Abstract

Background and Objectives The ability to correctly visualize the architectural arrangement of microvasculature is valuable to many diverse fields in medicine. In this study, we applied photoacoustics (PA) to obtain high-resolution images of submillimeter blood vessels. - Study Design/Materials and Methods: Short laser pulses are used to generate ultrasound from superficial blood vessels in several animal models. From these ultrasound waves the interior of blood vessels can be reconstructed. - Result : We present results from a novel approach based on the PA principle that allows specific in vivo visualization of dermal blood vessels without the use of contrast agents or ionizing radiation. = Conclusions: We show PA images of externalized blood vessels and demonstrate in vivo PA imaging of vasculature through layers of skin varying in thickness. Lasers Surg. Med. 35:354-362, 2004.

Original language	Undefined
Pages (from-to)	354-362
Number of pages	9
Journal	Lasers in surgery and medicine
Volume	35
Issue number	5
DOIs	https://doi.org/10.1002/lsm.20100
Publication status	Published - 2004

Keywords

Skin
METIS-220644
epigastric flap
Optoacoustics
3-D imaging
vascular anatomy
plastic surgery
microvasculature
IR-71983

Access to Document

10.1002/lsm.20100

Cite this

@article{a440e4b740454720911eaf59ee5c5072,

title = "Imaging of Small Vessels Using Photoacoustics: An In Vivo Study",

abstract = "Background and Objectives The ability to correctly visualize the architectural arrangement of microvasculature is valuable to many diverse fields in medicine. In this study, we applied photoacoustics (PA) to obtain high-resolution images of submillimeter blood vessels. - Study Design/Materials and Methods: Short laser pulses are used to generate ultrasound from superficial blood vessels in several animal models. From these ultrasound waves the interior of blood vessels can be reconstructed. - Result : We present results from a novel approach based on the PA principle that allows specific in vivo visualization of dermal blood vessels without the use of contrast agents or ionizing radiation. = Conclusions: We show PA images of externalized blood vessels and demonstrate in vivo PA imaging of vasculature through layers of skin varying in thickness. Lasers Surg. Med. 35:354-362, 2004.",

keywords = "Skin, METIS-220644, epigastric flap, Optoacoustics, 3-D imaging, vascular anatomy, plastic surgery, microvasculature, IR-71983",

author = "Siphanto, {Ronald I.} and R.G.M. Kolkman and A. Huisjes and M.H. Pilatou and {de Mul}, F.F.M. and Wiendelt Steenbergen and {van Adrichem}, {Leon N.A.}",

year = "2004",

doi = "10.1002/lsm.20100",

language = "Undefined",

volume = "35",

pages = "354--362",

journal = "Lasers in surgery and medicine",

issn = "0196-8092",

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TY - JOUR

T1 - Imaging of Small Vessels Using Photoacoustics: An In Vivo Study

AU - Siphanto, Ronald I.

AU - Kolkman, R.G.M.

AU - Huisjes, A.

AU - Pilatou, M.H.

AU - de Mul, F.F.M.

AU - Steenbergen, Wiendelt

AU - van Adrichem, Leon N.A.

PY - 2004

Y1 - 2004

N2 - Background and Objectives The ability to correctly visualize the architectural arrangement of microvasculature is valuable to many diverse fields in medicine. In this study, we applied photoacoustics (PA) to obtain high-resolution images of submillimeter blood vessels. - Study Design/Materials and Methods: Short laser pulses are used to generate ultrasound from superficial blood vessels in several animal models. From these ultrasound waves the interior of blood vessels can be reconstructed. - Result : We present results from a novel approach based on the PA principle that allows specific in vivo visualization of dermal blood vessels without the use of contrast agents or ionizing radiation. = Conclusions: We show PA images of externalized blood vessels and demonstrate in vivo PA imaging of vasculature through layers of skin varying in thickness. Lasers Surg. Med. 35:354-362, 2004.

AB - Background and Objectives The ability to correctly visualize the architectural arrangement of microvasculature is valuable to many diverse fields in medicine. In this study, we applied photoacoustics (PA) to obtain high-resolution images of submillimeter blood vessels. - Study Design/Materials and Methods: Short laser pulses are used to generate ultrasound from superficial blood vessels in several animal models. From these ultrasound waves the interior of blood vessels can be reconstructed. - Result : We present results from a novel approach based on the PA principle that allows specific in vivo visualization of dermal blood vessels without the use of contrast agents or ionizing radiation. = Conclusions: We show PA images of externalized blood vessels and demonstrate in vivo PA imaging of vasculature through layers of skin varying in thickness. Lasers Surg. Med. 35:354-362, 2004.

KW - Skin

KW - METIS-220644

KW - epigastric flap

KW - Optoacoustics

KW - 3-D imaging

KW - vascular anatomy

KW - plastic surgery

KW - microvasculature

KW - IR-71983

U2 - 10.1002/lsm.20100

DO - 10.1002/lsm.20100

M3 - Article

VL - 35

SP - 354

EP - 362

JO - Lasers in surgery and medicine

JF - Lasers in surgery and medicine

SN - 0196-8092

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ER -