Imaging of Small Vessels Using Photoacoustics: An In Vivo Study

Ronald I. Siphanto, R.G.M. Kolkman, A. Huisjes, M.H. Pilatou, F.F.M. de Mul, Wiendelt Steenbergen, Leon N.A. van Adrichem

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Abstract

Background and Objectives The ability to correctly visualize the architectural arrangement of microvasculature is valuable to many diverse fields in medicine. In this study, we applied photoacoustics (PA) to obtain high-resolution images of submillimeter blood vessels. - Study Design/Materials and Methods: Short laser pulses are used to generate ultrasound from superficial blood vessels in several animal models. From these ultrasound waves the interior of blood vessels can be reconstructed. - Result : We present results from a novel approach based on the PA principle that allows specific in vivo visualization of dermal blood vessels without the use of contrast agents or ionizing radiation. = Conclusions: We show PA images of externalized blood vessels and demonstrate in vivo PA imaging of vasculature through layers of skin varying in thickness. Lasers Surg. Med. 35:354-362, 2004.
Original languageUndefined
Pages (from-to)354-362
Number of pages9
JournalLasers in surgery and medicine
Volume35
Issue number5
DOIs
Publication statusPublished - 2004

Keywords

  • Skin
  • METIS-220644
  • epigastric flap
  • Optoacoustics
  • 3-D imaging
  • vascular anatomy
  • plastic surgery
  • microvasculature
  • IR-71983

Cite this

Siphanto, R. I., Kolkman, R. G. M., Huisjes, A., Pilatou, M. H., de Mul, F. F. M., Steenbergen, W., & van Adrichem, L. N. A. (2004). Imaging of Small Vessels Using Photoacoustics: An In Vivo Study. Lasers in surgery and medicine, 35(5), 354-362. https://doi.org/10.1002/lsm.20100