Abstract
Here, we report a robust platform for multi-modal analysis of immuno-captured individual extracellular vesicles (EVs). Stainless steel substrates were surface-modified to covalently immobilize specific antibodies targeting proteins found on EVs. Using PDMS microchannels, EVs were selectively captured on the substrates. Next, individual EVs were retraced and correlatively characterized here using SEM, AFM and Raman Spectroscopy.
| Original language | English |
|---|---|
| Title of host publication | MicroTas 2018 |
| Subtitle of host publication | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Editors | Fan-Gang Tseng, Gwo-Bin Lee |
| Publisher | The Chemical and Biological Microsystems Society |
| Pages | 2402-2403 |
| Number of pages | 2 |
| ISBN (Electronic) | 978-1-510-89757-1 |
| ISBN (Print) | 978-0-578-40530-8 |
| Publication status | Published - 11 Nov 2018 |
| Event | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan Duration: 10 Nov 2018 → 15 Nov 2018 Conference number: 22 https://cbmsociety.org/conferences/microtas2018/ |
Conference
| Conference | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 |
|---|---|
| Abbreviated title | MicroTAS 2018 |
| Country/Territory | Taiwan |
| City | Kaohsiung |
| Period | 10/11/18 → 15/11/18 |
| Internet address |
Keywords
- Extracellular vesicles
- AFM
- SEM
- Raman
- Correlative light
- Electron and probe microscopy
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