Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates

Felicia Ungureanu; Dorothee Wasserberg; Ni Yang; Remco Verdoold; Rob P.H. Kooyman

doi:10.1016/j.snb.2010.08.044

Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates

Felicia Ungureanu^*
, Dorothee Wasserberg
, Ni Yang
, Remco Verdoold
, Rob P.H. Kooyman

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

Abstract

A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40% of the available binding sites while reference data showed less than 0.05% binding. Endpoint SEM images of the sample and reference binding couples corroborate our findings.

Original language	English
Pages (from-to)	529-536
Number of pages	8
Journal	Sensors and Actuators, B: Chemical
Volume	150
Issue number	2
DOIs	https://doi.org/10.1016/j.snb.2010.08.044
Publication status	Published - 28 Oct 2010

Keywords

Affinity constant
Colorimetric darkfield microscopy
Gold nanoparticles
Immunosensor
Parallel detection

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10.1016/j.snb.2010.08.044

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title = "Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates",

abstract = "A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40\% of the available binding sites while reference data showed less than 0.05\% binding. Endpoint SEM images of the sample and reference binding couples corroborate our findings.",

keywords = "Affinity constant, Colorimetric darkfield microscopy, Gold nanoparticles, Immunosensor, Parallel detection",

author = "Felicia Ungureanu and Dorothee Wasserberg and Ni Yang and Remco Verdoold and Kooyman, \{Rob P.H.\}",

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AU - Ungureanu, Felicia

AU - Wasserberg, Dorothee

AU - Yang, Ni

AU - Verdoold, Remco

AU - Kooyman, Rob P.H.

PY - 2010/10/28

Y1 - 2010/10/28

N2 - A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40% of the available binding sites while reference data showed less than 0.05% binding. Endpoint SEM images of the sample and reference binding couples corroborate our findings.

AB - A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40% of the available binding sites while reference data showed less than 0.05% binding. Endpoint SEM images of the sample and reference binding couples corroborate our findings.

KW - Affinity constant

KW - Colorimetric darkfield microscopy

KW - Gold nanoparticles

KW - Immunosensor

KW - Parallel detection

UR - https://www.scopus.com/pages/publications/77958467770

U2 - 10.1016/j.snb.2010.08.044

DO - 10.1016/j.snb.2010.08.044

M3 - Article

AN - SCOPUS:77958467770

SN - 0925-4005

VL - 150

SP - 529

EP - 536

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

IS - 2

ER -

Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates

Abstract

Keywords

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