The combination of current up to 50 kA and magnetic field of 13 T in the Cable-In-Conduit Conductors (CICC) for the coils in the International Thermonuclear Experimental Reactor (ITER), cause huge local transverse forces. This results in changes in the transport properties, friction and anomalous contact resistance versus force behavior. The latest design optimizations tend to go toward a lower void fraction (VF). This has an impact on the evolution of the coupling loss and on the possible degree of strand bending and deformation. Toroidal Field Model Coil (TFMC) type of conductors with VFs of 26%, 30% and 36% respectively, are tested in the Twente Cable Press, by which a variable (cyclic) transverse force of 650 kN/m is transferred directly to a cable section of 400 mm length at 4.2 K. The AC loss of the conductor, the inter-strand and strand-bundle resistance (R/sub c/) in the cable and the associated bundle deformation are examined during mechanical cycling. The test results are discussed in view of the previous results on Nb/sub 3/Sn ITER CICCs.