Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus

Herke Jan Noordmans; Pieter Den Van Biesen; Rowland De Roode; Rudolf Verdaasdonk

doi:10.1117/12.762978

Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus

Herke Jan Noordmans, Pieter Den Van Biesen, Rowland De Roode, Rudolf Verdaasdonk

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

An interactive image matching program has been developed to help ophthalmologists in perceiving subtle differences between sequential images obtained during fluorescein angiography. In a pilot experiment, it appeared that the image matching program could effectively correct camera alignment errors. By offering simple tools like image overlay, blinking and image subtraction, differences between angiograms can be greatly enhanced and interpreted. It appeared that newly formed, leaking blood vessels could be detected at an earlier stage of the disease process using these tools. Treatment can be initiated right away, thereby preventing the patient from having additional visual loss. The matching program seems to improve the quality of fundus diagnostics but needs to be validated in future studies.

Original language	English
Title of host publication	Ophthalmic Technologies XVIII
DOIs	https://doi.org/10.1117/12.762978
Publication status	Published - 26 May 2008
Externally published	Yes
Event	Ophthalmic Technologies XVIII 2008 - San Jose, United States Duration: 19 Jan 2008 → 21 Jan 2008 Conference number: 18

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	6844
ISSN (Print)	1605-7422

Conference

Conference	Ophthalmic Technologies XVIII 2008
Country	United States
City	San Jose
Period	19/01/08 → 21/01/08

Keywords

Fundus imaging
Image registration
Ophthalmology
Retina images

Access to Document

10.1117/12.762978

68440GFinal published version, 601 KB

Link to publication in Scopus

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Cite this

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title = "Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus",

abstract = "An interactive image matching program has been developed to help ophthalmologists in perceiving subtle differences between sequential images obtained during fluorescein angiography. In a pilot experiment, it appeared that the image matching program could effectively correct camera alignment errors. By offering simple tools like image overlay, blinking and image subtraction, differences between angiograms can be greatly enhanced and interpreted. It appeared that newly formed, leaking blood vessels could be detected at an earlier stage of the disease process using these tools. Treatment can be initiated right away, thereby preventing the patient from having additional visual loss. The matching program seems to improve the quality of fundus diagnostics but needs to be validated in future studies.",

keywords = "Fundus imaging, Image registration, Ophthalmology, Retina images",

author = "Noordmans, {Herke Jan} and {Van Biesen}, {Pieter Den} and {De Roode}, Rowland and Rudolf Verdaasdonk",

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Noordmans, HJ, Van Biesen, PD, De Roode, R & Verdaasdonk, R 2008, Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus. in Ophthalmic Technologies XVIII., 68440G, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6844, Ophthalmic Technologies XVIII 2008, San Jose, United States, 19/01/08. https://doi.org/10.1117/12.762978

Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus. / Noordmans, Herke Jan; Van Biesen, Pieter Den; De Roode, Rowland; Verdaasdonk, Rudolf.

Ophthalmic Technologies XVIII. 2008. 68440G (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6844).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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