Improved precision using internal standards in disposable point-of-care capillary electrophoresis devices

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    Abstract

    This paper presents a systematic investigation of the viability of using internal standards to correct for chip-to-chip imprecision in disposable microchip capillary electrophoresis (μCE) devices. The effects of two internal standards (CsCl and LiCl) on the reproducibility of Na quantification were explored using in-house fabricated microchips. Five concentrations of NaCl were analyzed consecutively over five days, resulting in a dataset of 900 electropherograms with which to draw reliable conclusions from. We find internal standards can strongly improve the precision of disposable devices.
    Original languageUndefined
    Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
    Place of PublicationSan Diego
    PublisherChemical and Biochemical Society
    Pages2405-2407
    Number of pages3
    ISBN (Print)978-0-9798064-7-6
    Publication statusPublished - 26 Oct 2014
    Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - Henry B. Gonzalez Convention Center, San Antonio, United States
    Duration: 26 Oct 201430 Oct 2014
    Conference number: 18

    Publication series

    NameMicroTAS 2014
    PublisherChemical and Biochemical Society
    ISSN (Print)1556-5904

    Conference

    Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
    Abbreviated titleMicroTAS 2014
    CountryUnited States
    CitySan Antonio
    Period26/10/1430/10/14

    Keywords

    • EWI-25609
    • METIS-309841
    • IR-93841

    Cite this