Abstract
Enriching Circulating Tumor Cells (CTCs) from Diagnostic LeukApheresis (DLA) samples via optimized magnetic flow separation allows for processing larger aliquots of DLA while using less reagents.
In this way, a much larger number of CTCs can be obtained, with which the diagnoses and treatment of cancer patients can be improved.
Fluorescence images of the enriched cells can be efficiently segmented using StarDist and the detected cells can be individually isolated using a magnetic microneedle.
In this way, a much larger number of CTCs can be obtained, with which the diagnoses and treatment of cancer patients can be improved.
Fluorescence images of the enriched cells can be efficiently segmented using StarDist and the detected cells can be individually isolated using a magnetic microneedle.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Supervisors/Advisors |
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Award date | 8 Dec 2023 |
Place of Publication | Enschede |
Publisher | |
Print ISBNs | 978-90-365-5908-9 |
Electronic ISBNs | 978-90-365-5909-6 |
DOIs | |
Publication status | Published - 8 Dec 2023 |