Improving early cycle economic evaluation of diagnostic technologies

Lotte Maria Gertruda Steuten, Scott D. Ramsey

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)


The rapidly increasing range and expense of new diagnostics, compels consideration of a different, more proactive approach to health economic evaluation of diagnostic technologies. Early cycle economic evaluation is a decision analytic approach to evaluate technologies in development so as to increase the return on investment as well as patient and societal impact. This paper describes examples of ‘early cycle economic evaluations’ as applied to diagnostic technologies and highlights challenges in its real-time application. It shows that especially in the field of diagnostics, with rapid technological developments and a changing regulatory climate, early cycle economic evaluation can have a guiding role to improve the efficiency of the diagnostics innovation process. In the next five years the attention will move beyond the methodological and analytic challenges of early cycle economic evaluation towards the challenge of effectively applying it to improve diagnostic research and development and patient value. Future work in this area should therefore be ‘strong on principles and soft on metrics’, that is, the metrics that resonate most clearly with the various decision makers in this field
Original languageEnglish
Pages (from-to)491-498
JournalExpert review of pharmacoeconomics & outcomes research
Issue number4
Publication statusPublished - 2014


  • IR-91641
  • METIS-304828


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