Improving liquid chromatography efficiency: channels structured with micro-pillars

Mauro De Pra, Wim Th. Kok, Johannes G.E. Gardeniers, Gert Desmet, Peter J. Schoenmakers

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

2 Citations (Scopus)
24 Downloads (Pure)

Abstract

Band dispersion has been measured in micromachined separation channels structured with orderly disposed cylindrical micropillars. It was found that with an optimal channel design the band broadening could be lower by a factor of 3 than in packed columns with a comparable particle size. The positioning of the row of pillars closest to the side wall was a decisive factor in influencing band broadening.
Original languageUndefined
Title of host publicationMicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
EditorsK.F Jensen, J. Han, D.J. Harrison, J. Voldman
Place of PublicationSan Diego, CA, USA
PublisherTransducer Research Foundation
Pages838-840
Number of pages3
ISBN (Print)9780974361116
Publication statusPublished - 9 Oct 2005
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005 - Boston, United States
Duration: 9 Oct 200513 Oct 2005
Conference number: 9

Publication series

NameMicro total analysis systems 2005
PublisherTransducer Research Foundation
Volume2

Conference

Conference9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005
Abbreviated titleMicroTAS
CountryUnited States
CityBoston
Period9/10/0513/10/05

Keywords

  • METIS-224698
  • Liquid Chromatography
  • EWI-19987
  • Band broadening
  • IR-76612
  • Micropillars

Cite this

De Pra, M., Kok, W. T., Gardeniers, J. G. E., Desmet, G., & Schoenmakers, P. J. (2005). Improving liquid chromatography efficiency: channels structured with micro-pillars. In K. F. Jensen, J. Han, D. J. Harrison, & J. Voldman (Eds.), MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 838-840). (Micro total analysis systems 2005; Vol. 2). San Diego, CA, USA: Transducer Research Foundation.