Improving liquid chromatography efficiency: channels structured with micro-pillars

Mauro De Pra; Wim Th. Kok; Johannes G.E. Gardeniers; Gert Desmet; Peter J. Schoenmakers

Improving liquid chromatography efficiency: channels structured with micro-pillars

Mauro De Pra, Wim Th. Kok, Johannes G.E. Gardeniers, Gert Desmet, Peter J. Schoenmakers

Mesoscale Chemical Systems

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

2 Citations (Scopus)

54 Downloads (Pure)

Abstract

Band dispersion has been measured in micromachined separation channels structured with orderly disposed cylindrical micropillars. It was found that with an optimal channel design the band broadening could be lower by a factor of 3 than in packed columns with a comparable particle size. The positioning of the row of pillars closest to the side wall was a decisive factor in influencing band broadening.

Original language	Undefined
Title of host publication	MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Editors	K.F Jensen, J. Han, D.J. Harrison, J. Voldman
Place of Publication	San Diego, CA, USA
Publisher	Transducer Research Foundation
Pages	838-840
Number of pages	3
ISBN (Print)	9780974361116
Publication status	Published - 9 Oct 2005
Event	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005 - Boston, United States Duration: 9 Oct 2005 → 13 Oct 2005 Conference number: 9

Publication series

Name	Micro total analysis systems 2005
Publisher	Transducer Research Foundation
Volume	2

Conference

Conference	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005
Abbreviated title	MicroTAS
Country/Territory	United States
City	Boston
Period	9/10/05 → 13/10/05

Keywords

METIS-224698
Liquid Chromatography
EWI-19987
Band broadening
IR-76612
Micropillars

Access to Document

Cite this

De Pra, M., Kok, W. T., Gardeniers, J. G. E., Desmet, G., & Schoenmakers, P. J. (2005). Improving liquid chromatography efficiency: channels structured with micro-pillars. In K. F. Jensen, J. Han, D. J. Harrison, & J. Voldman (Eds.), MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 838-840). (Micro total analysis systems 2005; Vol. 2). Transducer Research Foundation.

De Pra, Mauro ; Kok, Wim Th. ; Gardeniers, Johannes G.E. et al. / Improving liquid chromatography efficiency: channels structured with micro-pillars. MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. editor / K.F Jensen ; J. Han ; D.J. Harrison ; J. Voldman. San Diego, CA, USA : Transducer Research Foundation, 2005. pp. 838-840 (Micro total analysis systems 2005).

@inproceedings{0242826ad0bc4cbd9c8917e03268616f,

title = "Improving liquid chromatography efficiency: channels structured with micro-pillars",

abstract = "Band dispersion has been measured in micromachined separation channels structured with orderly disposed cylindrical micropillars. It was found that with an optimal channel design the band broadening could be lower by a factor of 3 than in packed columns with a comparable particle size. The positioning of the row of pillars closest to the side wall was a decisive factor in influencing band broadening.",

keywords = "METIS-224698, Liquid Chromatography, EWI-19987, Band broadening, IR-76612, Micropillars",

author = "{De Pra}, Mauro and Kok, {Wim Th.} and Gardeniers, {Johannes G.E.} and Gert Desmet and Schoenmakers, {Peter J.}",

year = "2005",

month = oct,

day = "9",

language = "Undefined",

isbn = "9780974361116",

series = "Micro total analysis systems 2005",

publisher = "Transducer Research Foundation",

pages = "838--840",

editor = "K.F Jensen and J. Han and D.J. Harrison and J. Voldman",

booktitle = "MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

note = "9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005 ; Conference date: 09-10-2005 Through 13-10-2005",

}

De Pra, M, Kok, WT, Gardeniers, JGE, Desmet, G & Schoenmakers, PJ 2005, Improving liquid chromatography efficiency: channels structured with micro-pillars. in KF Jensen, J Han, DJ Harrison & J Voldman (eds), MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Micro total analysis systems 2005, vol. 2, Transducer Research Foundation, San Diego, CA, USA, pp. 838-840, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005, Boston, Massachusetts, United States, 9/10/05.

Improving liquid chromatography efficiency: channels structured with micro-pillars. / De Pra, Mauro; Kok, Wim Th.; Gardeniers, Johannes G.E. et al.
MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. ed. / K.F Jensen; J. Han; D.J. Harrison; J. Voldman. San Diego, CA, USA: Transducer Research Foundation, 2005. p. 838-840 (Micro total analysis systems 2005; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Improving liquid chromatography efficiency: channels structured with micro-pillars

AU - De Pra, Mauro

AU - Kok, Wim Th.

AU - Gardeniers, Johannes G.E.

AU - Desmet, Gert

AU - Schoenmakers, Peter J.

N1 - Conference code: 9

PY - 2005/10/9

Y1 - 2005/10/9

N2 - Band dispersion has been measured in micromachined separation channels structured with orderly disposed cylindrical micropillars. It was found that with an optimal channel design the band broadening could be lower by a factor of 3 than in packed columns with a comparable particle size. The positioning of the row of pillars closest to the side wall was a decisive factor in influencing band broadening.

AB - Band dispersion has been measured in micromachined separation channels structured with orderly disposed cylindrical micropillars. It was found that with an optimal channel design the band broadening could be lower by a factor of 3 than in packed columns with a comparable particle size. The positioning of the row of pillars closest to the side wall was a decisive factor in influencing band broadening.

KW - METIS-224698

KW - Liquid Chromatography

KW - EWI-19987

KW - Band broadening

KW - IR-76612

KW - Micropillars

M3 - Conference contribution

SN - 9780974361116

T3 - Micro total analysis systems 2005

SP - 838

EP - 840

BT - MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

A2 - Jensen, K.F

A2 - Han, J.

A2 - Harrison, D.J.

A2 - Voldman, J.

PB - Transducer Research Foundation

CY - San Diego, CA, USA

T2 - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2005

Y2 - 9 October 2005 through 13 October 2005

ER -

De Pra M, Kok WT, Gardeniers JGE, Desmet G, Schoenmakers PJ. Improving liquid chromatography efficiency: channels structured with micro-pillars. In Jensen KF, Han J, Harrison DJ, Voldman J, editors, MicroTAS 2005 Conference - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. San Diego, CA, USA: Transducer Research Foundation. 2005. p. 838-840. (Micro total analysis systems 2005).