Improving the CellSearch® system

Joost Franciscus Swennenhuis; Guus van Dalum; Leonie Laura Zeune; Leonardus Wendelinus Mathias Marie Terstappen

doi:10.1080/14737159.2016.1255144

Improving the CellSearch® system

Joost Franciscus Swennenhuis, Guus van Dalum, Leonie Laura Zeune, Leonardus Wendelinus Mathias Marie Terstappen

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Introduction: The CellSearch® CTC test enumerates tumor cells present in 7.5 ml blood of cancer patients. improvements, extensions and different utilities of the cellsearch system are discussed in this paper. Areas covered: This paper describes work performed with the CellSearch system, which go beyond the normal scope of the test. All results from searches with the search term ‘CellSearch’ from Web of Science and PubMed were categorized and discussed. Expert commentary: The CellSearch Circulating Tumor Cell test captures and identifies tumor cells in blood that are associated with poor clinical outcome. How to best use CTC in clinical practice is being explored in many clinical trials. The ability to extract information from the CTC to guide therapy will expand the potential clinical utility of CTC.

Original language	English
Pages (from-to)	1291-1305
Journal	Expert review of molecular diagnostics
Volume	16
Issue number	12
DOIs	https://doi.org/10.1080/14737159.2016.1255144
Publication status	Published - 2016

Keywords

IR-103827
METIS-318839

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/14737159.2016.1255144

_30_-_3_-_2017_ImprovingFinal published version, 2.24 MB

Cite this

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title = "Improving the CellSearch{\textregistered} system",

abstract = "Introduction: The CellSearch{\textregistered} CTC test enumerates tumor cells present in 7.5 ml blood of cancer patients. improvements, extensions and different utilities of the cellsearch system are discussed in this paper. Areas covered: This paper describes work performed with the CellSearch system, which go beyond the normal scope of the test. All results from searches with the search term {\textquoteleft}CellSearch{\textquoteright} from Web of Science and PubMed were categorized and discussed. Expert commentary: The CellSearch Circulating Tumor Cell test captures and identifies tumor cells in blood that are associated with poor clinical outcome. How to best use CTC in clinical practice is being explored in many clinical trials. The ability to extract information from the CTC to guide therapy will expand the potential clinical utility of CTC.",

keywords = "IR-103827, METIS-318839",

author = "Swennenhuis, {Joost Franciscus} and {van Dalum}, Guus and Zeune, {Leonie Laura} and Terstappen, {Leonardus Wendelinus Mathias Marie}",

note = "Open access ",

year = "2016",

doi = "10.1080/14737159.2016.1255144",

language = "English",

volume = "16",

pages = "1291--1305",

journal = "Expert review of molecular diagnostics",

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AU - Swennenhuis, Joost Franciscus

AU - van Dalum, Guus

AU - Zeune, Leonie Laura

AU - Terstappen, Leonardus Wendelinus Mathias Marie

N1 - Open access

PY - 2016

Y1 - 2016

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AB - Introduction: The CellSearch® CTC test enumerates tumor cells present in 7.5 ml blood of cancer patients. improvements, extensions and different utilities of the cellsearch system are discussed in this paper. Areas covered: This paper describes work performed with the CellSearch system, which go beyond the normal scope of the test. All results from searches with the search term ‘CellSearch’ from Web of Science and PubMed were categorized and discussed. Expert commentary: The CellSearch Circulating Tumor Cell test captures and identifies tumor cells in blood that are associated with poor clinical outcome. How to best use CTC in clinical practice is being explored in many clinical trials. The ability to extract information from the CTC to guide therapy will expand the potential clinical utility of CTC.

KW - IR-103827

KW - METIS-318839

U2 - 10.1080/14737159.2016.1255144

DO - 10.1080/14737159.2016.1255144

M3 - Article

SN - 1473-7159

VL - 16

SP - 1291

EP - 1305

JO - Expert review of molecular diagnostics

JF - Expert review of molecular diagnostics

IS - 12

ER -

Improving the CellSearch® system

Abstract

Keywords

UN SDGs

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