In-line Sensing of Sodium Ascorbate Using a Poly(ferrocenylsilane)-coated Microfluidic Device

B.D. Kieviet, Lionel Dos Ramos, Mark A. Hempenius, Joost Duvigneau, Peter Manfred Schön, Gyula J. Vancso

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

Poly(ferrocenylsilane) (PFS) is a redox-active polymer that can be utilized in a variety of applications, such as sensing, nanoparticle foundries or dual-responsive hydrogels, due to the fact that it can be partially or completely oxidized, reversibly, by (electro)chemical means. In this research, PFS is tethered to a cysteamine-modified gold-coated microchannel electrode via amine alkylation, following a recent published procedure for conventional macro-sized electrodes. The PFS-coated microfluidic device is successfully employed as an electrochemical sensor for sodium l-ascorbate, or vitamin C, with a detection limit of 0.5 mM in aqueous solution. The fabrication of the device, that comprises gold-coated electrodes of micrometers in width, is discussed, as well as the static and in-line detection of sodium l-ascorbate. The analyte concentration is sensed through an electrocatalytic process in both static and in-line cases, by cyclic voltammetry and amperometry, respectively. The findings presented in this work open novel opportunities for local surface modification of chip-integrated gold electrodes by redox-responsive polymers used, e.g., as electrochemical sensors.
Original languageEnglish
Pages (from-to)337-343
JournalEuropean polymer journal
Volume83
DOIs
Publication statusPublished - 26 Aug 2016

Keywords

  • IR-101771
  • METIS-318037

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