In-situ photopatterning of hydrogel microarrays in polished microchips

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    Abstract

    We present a fabrication method which enables simple and eproducible photopatterning of micron- sized hydrogel arrays inside closed microchips. To achieve this, the glass cover of the microchip is thinned by mechanical grinding and polishing. This procedure reduces the spacing between the photomask and hydrogel precursor and thereby the effects of UV diffraction. We demonstrate the effects of glass cover thickness and roughness, together with different optical lithography recipes on patterning success. The patterning method is tested with two different types of photopolymerizing hydrogels, polyacrylamide and polyethylene glycol diacrylate. The presented method enables in-situ fabrication of welldefined hydrogel patterns for microfluidic platforms
    Original languageUndefined
    Title of host publicationThe 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS 2015)
    Place of PublicationGyeongju, Korea
    PublisherChemical and Biological Micro Systems Society
    Pages1463-1465
    Number of pages3
    ISBN (Print)978-0-9798064-8-3
    Publication statusPublished - 25 Oct 2015
    Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2015 - Hwabaek International Convention Center (HICO), Gyeongju, Korea, Republic of
    Duration: 25 Oct 201529 Oct 2015
    Conference number: 19
    http://www.rsc.org/images/LOC/2015/PDFs/Copyrite.pdf

    Publication series

    NameProceedings International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS
    PublisherChemical and Biological Microsystems Society
    ISSN (Print)1556-5904

    Conference

    Conference19th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2015
    Abbreviated titleMicroTas 2015
    CountryKorea, Republic of
    CityGyeongju
    Period25/10/1529/10/15
    Internet address

    Keywords

    • EWI-26554
    • METIS-315088
    • IR-98703

    Cite this

    Gümüscü, B., van den Berg, A., & Eijkel, J. C. T. (2015). In-situ photopatterning of hydrogel microarrays in polished microchips. In The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS 2015) (pp. 1463-1465). (Proceedings International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS). Gyeongju, Korea: Chemical and Biological Micro Systems Society.