In-vitro and clinical evaluation of transurethral laser-induced prostatectomy (TULIP)

Christiaan F. Swol*, Rudolf M. Verdaasdonk, Jaap Mooibroek, Tom A. Boon

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

2 Citations (Scopus)

Abstract

Transurethral ultrasound-guided laser induced prostatectomy (TULIP) is a recent development in the treatment of benign prostatic hyperplasia. The system is based upon Nd:YAG laser irradiation delivered by a right angled fiber. The dosimetry used in a clinical situation is mostly based upon animal studies. In this study, the light and temperature distribution in the prostate during Nd:YAG laser irradiation were modeled using Monte Carlo and finite differences theory. The results of this model were compared with in vitro experiments. The influence of the different parameters involved, e.g., the scanning speed and the power of the laser beam, were evaluated. Initial results show the temperature distribution and thus the therapeutic effect of the TULIP procedure. Until now 36 patients have been treated successfully. The mean in-hospital time was somewhat shorter than for a TURP treatment while the results were comparable. These treatments, however, show the need for a better understanding of the mechanisms involved. Modeling and subsequent in vitro and in vivo measurements might improve the understanding and safe and successful application of prostate treatment using laser based systems.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSPIE
Pages79-87
Number of pages9
ISBN (Print)081941106X
DOIs
Publication statusPublished - 1 Jan 1993
Externally publishedYes
EventLasers in Urology, Gynecology, and General Surgery 1993 - Los Angeles, United States
Duration: 16 Jan 199318 Jan 1993

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1879
ISSN (Print)0277-786X

Conference

ConferenceLasers in Urology, Gynecology, and General Surgery 1993
CountryUnited States
CityLos Angeles
Period16/01/9318/01/93

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  • Cite this

    Swol, C. F., Verdaasdonk, R. M., Mooibroek, J., & Boon, T. A. (1993). In-vitro and clinical evaluation of transurethral laser-induced prostatectomy (TULIP). In Proceedings of SPIE - The International Society for Optical Engineering (pp. 79-87). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1879). SPIE. https://doi.org/10.1117/12.146222