In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

Astrid Maria Hoving; Jason Voorneveld; Julia Olegivna Mikhal; Johan G. Bosch; E. Groot Jebbink; Cornelis Herman Slump

doi:10.1117/1.JMI.8.1.017001

In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

Astrid Maria Hoving^*, Jason Voorneveld, Julia Olegivna Mikhal, Johan G. Bosch, E. Groot Jebbink, Cornelis Herman Slump

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

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Abstract

Purpose: Detailed blood flow studies may contribute to improvements in carotid artery stenting. High-frame-rate contrast-enhanced ultrasound followed by particle image velocimetry (PIV), also called echoPIV, is a technique to study blood flow patterns in detail. The performance of echoPIV in presence of a stent has not yet been studied extensively. We compared the performance of echoPIV in stented and nonstented regions in an in vitro flow setup.

Approach: A carotid artery stent was deployed in a vessel-mimicking phantom. High-frame-rate contrast-enhanced ultrasound images were acquired with various settings. Signal intensities of the contrast agent, velocity values, and flow profiles were calculated.

Results: The results showed decreased signal intensities and correlation coefficients inside the stent, however, PIV analysis in the stent still resulted in plausible flow vectors.

Conclusions: Velocity values and laminar flow profiles can be measured in vitro in stented arteries using echoPIV.

Original language	English
Article number	017001
Number of pages	16
Journal	Journal of medical imaging
Volume	8
Issue number	1
DOIs	https://doi.org/10.1117/1.JMI.8.1.017001
Publication status	Published - 13 Jan 2021

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@article{f3d92fc5fe9c4655ac5bf552d16e953b,

title = "In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent",

abstract = "Purpose: Detailed blood flow studies may contribute to improvements in carotid artery stenting. High-frame-rate contrast-enhanced ultrasound followed by particle image velocimetry (PIV), also called echoPIV, is a technique to study blood flow patterns in detail. The performance of echoPIV in presence of a stent has not yet been studied extensively. We compared the performance of echoPIV in stented and nonstented regions in an in vitro flow setup.Approach: A carotid artery stent was deployed in a vessel-mimicking phantom. High-frame-rate contrast-enhanced ultrasound images were acquired with various settings. Signal intensities of the contrast agent, velocity values, and flow profiles were calculated.Results: The results showed decreased signal intensities and correlation coefficients inside the stent, however, PIV analysis in the stent still resulted in plausible flow vectors.Conclusions: Velocity values and laminar flow profiles can be measured in vitro in stented arteries using echoPIV.",

author = "Hoving, {Astrid Maria} and Jason Voorneveld and Mikhal, {Julia Olegivna} and Bosch, {Johan G.} and {Groot Jebbink}, E. and Slump, {Cornelis Herman}",

note = "Funding Information: This research was financially supported by the Stichting TWIN (Foundation TWIN). The authors state no conflict of interest and have nothing to disclose. The authors would like to thank Bracco Suisse SA for providing BR14 microbubbles. Thanks to Henny Kuipers for his contributions to the design and fabrication of the flow setup, BMPI group for the use of their ultrasound equipment, and thanks to the ultrasound experts of Erasmus MC Thoraxcenter for the detailed technical help and feedback. Publisher Copyright: {\textcopyright} The Authors. Financial transaction number: 342101855 ",

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doi = "10.1117/1.JMI.8.1.017001",

language = "English",

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T1 - In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

AU - Hoving, Astrid Maria

AU - Voorneveld, Jason

AU - Mikhal, Julia Olegivna

AU - Bosch, Johan G.

AU - Groot Jebbink, E.

AU - Slump, Cornelis Herman

N1 - Funding Information: This research was financially supported by the Stichting TWIN (Foundation TWIN). The authors state no conflict of interest and have nothing to disclose. The authors would like to thank Bracco Suisse SA for providing BR14 microbubbles. Thanks to Henny Kuipers for his contributions to the design and fabrication of the flow setup, BMPI group for the use of their ultrasound equipment, and thanks to the ultrasound experts of Erasmus MC Thoraxcenter for the detailed technical help and feedback. Publisher Copyright: © The Authors. Financial transaction number: 342101855

PY - 2021/1/13

Y1 - 2021/1/13

N2 - Purpose: Detailed blood flow studies may contribute to improvements in carotid artery stenting. High-frame-rate contrast-enhanced ultrasound followed by particle image velocimetry (PIV), also called echoPIV, is a technique to study blood flow patterns in detail. The performance of echoPIV in presence of a stent has not yet been studied extensively. We compared the performance of echoPIV in stented and nonstented regions in an in vitro flow setup.Approach: A carotid artery stent was deployed in a vessel-mimicking phantom. High-frame-rate contrast-enhanced ultrasound images were acquired with various settings. Signal intensities of the contrast agent, velocity values, and flow profiles were calculated.Results: The results showed decreased signal intensities and correlation coefficients inside the stent, however, PIV analysis in the stent still resulted in plausible flow vectors.Conclusions: Velocity values and laminar flow profiles can be measured in vitro in stented arteries using echoPIV.

AB - Purpose: Detailed blood flow studies may contribute to improvements in carotid artery stenting. High-frame-rate contrast-enhanced ultrasound followed by particle image velocimetry (PIV), also called echoPIV, is a technique to study blood flow patterns in detail. The performance of echoPIV in presence of a stent has not yet been studied extensively. We compared the performance of echoPIV in stented and nonstented regions in an in vitro flow setup.Approach: A carotid artery stent was deployed in a vessel-mimicking phantom. High-frame-rate contrast-enhanced ultrasound images were acquired with various settings. Signal intensities of the contrast agent, velocity values, and flow profiles were calculated.Results: The results showed decreased signal intensities and correlation coefficients inside the stent, however, PIV analysis in the stent still resulted in plausible flow vectors.Conclusions: Velocity values and laminar flow profiles can be measured in vitro in stented arteries using echoPIV.

UR - https://doi.org/10.1117/1.JMI.8.1.017001

U2 - 10.1117/1.JMI.8.1.017001

DO - 10.1117/1.JMI.8.1.017001

M3 - Article

SN - 2329-4302

VL - 8

JO - Journal of medical imaging

JF - Journal of medical imaging

IS - 1

M1 - 017001

ER -

In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

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