In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics

Vamshi Damagatla; Siënna Karremans; Alessandro Bossi; Edoardo Martinenghi; Srirang Manohar; Paola Taroni; Rinaldo Cubeddu; Antonio Pifferi; Ilaria Bargigia

doi:10.1038/s41597-026-06586-9

In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics

Vamshi Damagatla
, Siënna Karremans
, Alessandro Bossi
, Edoardo Martinenghi
, Srirang Manohar
, Paola Taroni
, Rinaldo Cubeddu
, Antonio Pifferi^*
, Ilaria Bargigia

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We present a comprehensive dataset of absorption and reduced scattering spectra collected via time-domain diffuse optical spectroscopy in the 610-1110 nm range, across 10 subjects and on 5 different body locations – the upper arm, the radius-ulna region, the abdomen, the forehead, and the calcaneus. The ultrasound images acquired in the same location are included as well, and along with the demographic information shed useful insights on the inter-subject variability. The dataset, openly available in Zenodo, contains the raw data, the meta data, the tools to operate on them, and can be exploited to devise light-based diagnostics or therapeutic techniques, to appreciate biological variability, and also to test different models of photon migration.

Original language	English
Article number	261
Number of pages	13
Journal	Scientific Data
Volume	13
Issue number	1
Early online date	22 Jan 2026
DOIs	https://doi.org/10.1038/s41597-026-06586-9
Publication status	E-pub ahead of print/First online - 22 Jan 2026

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10.1038/s41597-026-06586-9Licence: CC BY-NC-ND

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abstract = "We present a comprehensive dataset of absorption and reduced scattering spectra collected via time-domain diffuse optical spectroscopy in the 610-1110 nm range, across 10 subjects and on 5 different body locations – the upper arm, the radius-ulna region, the abdomen, the forehead, and the calcaneus. The ultrasound images acquired in the same location are included as well, and along with the demographic information shed useful insights on the inter-subject variability. The dataset, openly available in Zenodo, contains the raw data, the meta data, the tools to operate on them, and can be exploited to devise light-based diagnostics or therapeutic techniques, to appreciate biological variability, and also to test different models of photon migration.",

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AU - Damagatla, Vamshi

AU - Karremans, Siënna

AU - Bossi, Alessandro

AU - Martinenghi, Edoardo

AU - Manohar, Srirang

AU - Taroni, Paola

AU - Cubeddu, Rinaldo

AU - Pifferi, Antonio

AU - Bargigia, Ilaria

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In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics

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In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics

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