In vivo photoacoustic imaging of blood vessels with a pulsed laser diode

R.G.M. Kolkman, Wiendelt Steenbergen, Ton van Leeuwen

Research output: Contribution to journalArticleAcademicpeer-review

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144 Downloads (Pure)

Abstract

Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. For this technique, usually large and costly Q-switched Nd:YAG lasers are used. These lasers provide a pulse energy of at least several milliJoules. In search of alternative light sources, we investigated the use of a small and compact pulsed laser diode to image blood vessels. We proved that a pulsed laser diode can be applied for imaging blood vessels in vivo.
Original languageUndefined
Pages (from-to)134-139
Number of pages6
JournalLasers in medical science
Volume21
Issue number3
DOIs
Publication statusPublished - 2006

Keywords

  • METIS-233953
  • IR-76436

Cite this

Kolkman, R.G.M. ; Steenbergen, Wiendelt ; van Leeuwen, Ton. / In vivo photoacoustic imaging of blood vessels with a pulsed laser diode. In: Lasers in medical science. 2006 ; Vol. 21, No. 3. pp. 134-139.
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In vivo photoacoustic imaging of blood vessels with a pulsed laser diode. / Kolkman, R.G.M.; Steenbergen, Wiendelt; van Leeuwen, Ton.

In: Lasers in medical science, Vol. 21, No. 3, 2006, p. 134-139.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - In vivo photoacoustic imaging of blood vessels with a pulsed laser diode

AU - Kolkman, R.G.M.

AU - Steenbergen, Wiendelt

AU - van Leeuwen, Ton

PY - 2006

Y1 - 2006

N2 - Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. For this technique, usually large and costly Q-switched Nd:YAG lasers are used. These lasers provide a pulse energy of at least several milliJoules. In search of alternative light sources, we investigated the use of a small and compact pulsed laser diode to image blood vessels. We proved that a pulsed laser diode can be applied for imaging blood vessels in vivo.

AB - Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. For this technique, usually large and costly Q-switched Nd:YAG lasers are used. These lasers provide a pulse energy of at least several milliJoules. In search of alternative light sources, we investigated the use of a small and compact pulsed laser diode to image blood vessels. We proved that a pulsed laser diode can be applied for imaging blood vessels in vivo.

KW - METIS-233953

KW - IR-76436

U2 - 10.1007/s10103-006-0384-z

DO - 10.1007/s10103-006-0384-z

M3 - Article

VL - 21

SP - 134

EP - 139

JO - Lasers in medical science

JF - Lasers in medical science

SN - 0268-8921

IS - 3

ER -