Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy

Holger Schönherr, M.W.J. Beulen, H.J. Bugler, Jurriaan Huskens, F.C.J.M. van Veggel, David Reinhoudt, Gyula J. Vancso

Research output: Contribution to journalArticleAcademicpeer-review

177 Citations (Scopus)

Abstract

Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.
Original languageUndefined
Pages (from-to)4963-4967
Number of pages5
JournalJournal of the American Chemical Society
Volume122
Issue number20
DOIs
Publication statusPublished - 2000

Keywords

  • METIS-106410
  • IR-11933

Cite this

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title = "Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy",
abstract = "Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.",
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year = "2000",
doi = "10.1021/ja994040i",
language = "Undefined",
volume = "122",
pages = "4963--4967",
journal = "Journal of the American Chemical Society",
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Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy. / Schönherr, Holger; Beulen, M.W.J.; Bugler, H.J.; Huskens, Jurriaan; van Veggel, F.C.J.M.; Reinhoudt, David; Vancso, Gyula J.

In: Journal of the American Chemical Society, Vol. 122, No. 20, 2000, p. 4963-4967.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy

AU - Schönherr, Holger

AU - Beulen, M.W.J.

AU - Bugler, H.J.

AU - Huskens, Jurriaan

AU - van Veggel, F.C.J.M.

AU - Reinhoudt, David

AU - Vancso, Gyula J.

PY - 2000

Y1 - 2000

N2 - Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.

AB - Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.

KW - METIS-106410

KW - IR-11933

U2 - 10.1021/ja994040i

DO - 10.1021/ja994040i

M3 - Article

VL - 122

SP - 4963

EP - 4967

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 20

ER -