Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy

Holger Schönherr; M.W.J. Beulen; H.J. Bugler; Jurriaan Huskens; F.C.J.M. van Veggel; David Reinhoudt; Gyula J. Vancso

doi:10.1021/ja994040i

Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy

Holger Schönherr, M.W.J. Beulen, H.J. Bugler, Jurriaan Huskens, F.C.J.M. van Veggel, David Reinhoudt, Gyula J. Vancso

Research output: Contribution to journal › Article › Academic › peer-review

190 Citations (Scopus)

Abstract

Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.

Original language	Undefined
Pages (from-to)	4963-4967
Number of pages	5
Journal	Journal of the American Chemical Society
Volume	122
Issue number	20
DOIs	https://doi.org/10.1021/ja994040i
Publication status	Published - 2000

Keywords

METIS-106410
IR-11933

Access to Document

10.1021/ja994040i

Cite this

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title = "Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy",

abstract = "Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.",

keywords = "METIS-106410, IR-11933",

author = "Holger Sch{\"o}nherr and M.W.J. Beulen and H.J. Bugler and Jurriaan Huskens and {van Veggel}, F.C.J.M. and David Reinhoudt and Vancso, {Gyula J.}",

year = "2000",

doi = "10.1021/ja994040i",

language = "Undefined",

volume = "122",

pages = "4963--4967",

journal = "Journal of the American Chemical Society",

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TY - JOUR

T1 - Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy

AU - Schönherr, Holger

AU - Beulen, M.W.J.

AU - Bugler, H.J.

AU - Huskens, Jurriaan

AU - van Veggel, F.C.J.M.

AU - Reinhoudt, David

AU - Vancso, Gyula J.

PY - 2000

Y1 - 2000

N2 - Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.

AB - Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferrocene moieties immobilized on atomic force microscopy tips and B-cyclodextrin receptors in highly ordered self-assembled monolayers on Au(111) was studied. The rupture force of individual ferrocene-B-cyclodextrin complexes was found to be 56 ± 10 pN. The value of this unbinding force was independent of the unloading rate. This was attributed to the fast (de)complexation kinetics of the host-guest complex.

KW - METIS-106410

KW - IR-11933

U2 - 10.1021/ja994040i

DO - 10.1021/ja994040i

M3 - Article

VL - 122

SP - 4963

EP - 4967

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 20

ER -