Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO

Michael Broomé; DW Donker

doi:10.1186/s12967-015-0760-1

Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO

Michael Broomé^*, DW Donker

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

8 Downloads (Pure)

Abstract

Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.

Original language	English
Article number	4
Journal	Journal of translational medicine
Volume	14
Issue number	1
DOIs	https://doi.org/10.1186/s12967-015-0760-1
Publication status	Published - 6 Jan 2016
Externally published	Yes

Keywords

Extracorporeal life support (ECLS)
Realtime cardiovascular computer simulation
Veno-arterial extracorporeal membrane oxygenation (ECMO)
Diastole
Cardiogenic shock
Extracorporeal Membrane Oxygenation
Heart failure
Heart Ventricles
Hemodynamics
Humans
Monitoring, Physiologic
Precision Medicine

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10.1186/s12967-015-0760-1Licence: CC BY

s12967-015-0760-1Final published version, 1.02 MBLicence: CC BY

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title = "Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO",

abstract = "Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.",

keywords = "Extracorporeal life support (ECLS), Realtime cardiovascular computer simulation, Veno-arterial extracorporeal membrane oxygenation (ECMO), Diastole, Cardiogenic shock, Extracorporeal Membrane Oxygenation, Heart failure, Heart Ventricles, Hemodynamics, Humans, Monitoring, Physiologic, Precision Medicine",

author = "Michael Broom{\'e} and DW Donker",

note = "Funding Information: This study was supported by a Grant No. 2012-2800 from the Swedish Research Council. Publisher Copyright: {\textcopyright} 2016 Broom{\'e} and Donker.",

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doi = "10.1186/s12967-015-0760-1",

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AU - Broomé, Michael

AU - Donker, DW

PY - 2016/1/6

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N2 - Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.

AB - Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.

KW - Extracorporeal life support (ECLS)

KW - Realtime cardiovascular computer simulation

KW - Veno-arterial extracorporeal membrane oxygenation (ECMO)

KW - Diastole

KW - Cardiogenic shock

KW - Extracorporeal Membrane Oxygenation

KW - Heart failure

KW - Heart Ventricles

KW - Hemodynamics

KW - Humans

KW - Monitoring, Physiologic

KW - Precision Medicine

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DO - 10.1186/s12967-015-0760-1

M3 - Article

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VL - 14

JO - Journal of translational medicine

JF - Journal of translational medicine

IS - 1

M1 - 4

ER -

Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO

Abstract

Keywords

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