Influence of Cardiac Risk Factors and Medication on Length of Hospitalization in Patients Undergoing Major Vascular Surgery

Marleen A. van de Pol, Mark van Houdenhoven, Elias W. Hans, Eric Boersma, Jeroen J. Bax, Harm H.H. Feringa, Olaf Schouten, Marc r.H.M. van Sambeek, Don Poldermans

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Abstract

Major vascular surgery is associated with a long in-hospital length of stay (LOS). Cardiac risk factors identify patients with an increased risk. Recent studies have associated statin, aspirin, and β-blocker therapies with improved postoperative outcome. However, the effect of all these factors on LOS has not been defined. Our aims were to determine the effect of cardiac risk factors and (preventive) statin, aspirin, and β-blocker therapy on LOS and to deduce from these factors a model that predicts LOS. In total, 2,374 patients from 1990 to 2004 were enrolled. Mean LOS was 18 ± 9 days. Cardiac risk factors that were significantly associated with LOS in the multivariable analysis were age, previous heart failure, hypertension, diabetes mellitus, renal failure, and chronic obstructive pulmonary disease. Statin and aspirin use was associated with a shorter LOS. Beta blockers shortened LOS only in patients with underlying coronary artery disease. Together, these factors explained 14.1% of the variance in LOS. In conclusion, in-hospital LOS in patients who undergo major vascular surgery can be predicted more accurately by clinical cardiac risk factors. A significant decrease in in-hospital LOS was achieved with statin, aspirin, and β-blocker therapies.
Original languageUndefined
Pages (from-to)1423-1426
JournalAmerican journal of cardiology
Volume97
Issue number10
DOIs
Publication statusPublished - 2006

Keywords

  • IR-78506

Cite this

van de Pol, Marleen A. ; van Houdenhoven, Mark ; Hans, Elias W. ; Boersma, Eric ; Bax, Jeroen J. ; Feringa, Harm H.H. ; Schouten, Olaf ; van Sambeek, Marc r.H.M. ; Poldermans, Don. / Influence of Cardiac Risk Factors and Medication on Length of Hospitalization in Patients Undergoing Major Vascular Surgery. In: American journal of cardiology. 2006 ; Vol. 97, No. 10. pp. 1423-1426.
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abstract = "Major vascular surgery is associated with a long in-hospital length of stay (LOS). Cardiac risk factors identify patients with an increased risk. Recent studies have associated statin, aspirin, and β-blocker therapies with improved postoperative outcome. However, the effect of all these factors on LOS has not been defined. Our aims were to determine the effect of cardiac risk factors and (preventive) statin, aspirin, and β-blocker therapy on LOS and to deduce from these factors a model that predicts LOS. In total, 2,374 patients from 1990 to 2004 were enrolled. Mean LOS was 18 ± 9 days. Cardiac risk factors that were significantly associated with LOS in the multivariable analysis were age, previous heart failure, hypertension, diabetes mellitus, renal failure, and chronic obstructive pulmonary disease. Statin and aspirin use was associated with a shorter LOS. Beta blockers shortened LOS only in patients with underlying coronary artery disease. Together, these factors explained 14.1{\%} of the variance in LOS. In conclusion, in-hospital LOS in patients who undergo major vascular surgery can be predicted more accurately by clinical cardiac risk factors. A significant decrease in in-hospital LOS was achieved with statin, aspirin, and β-blocker therapies.",
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van de Pol, MA, van Houdenhoven, M, Hans, EW, Boersma, E, Bax, JJ, Feringa, HHH, Schouten, O, van Sambeek, MRHM & Poldermans, D 2006, 'Influence of Cardiac Risk Factors and Medication on Length of Hospitalization in Patients Undergoing Major Vascular Surgery' American journal of cardiology, vol. 97, no. 10, pp. 1423-1426. https://doi.org/10.1016/j.amjcard.2005.12.032

Influence of Cardiac Risk Factors and Medication on Length of Hospitalization in Patients Undergoing Major Vascular Surgery. / van de Pol, Marleen A.; van Houdenhoven, Mark; Hans, Elias W.; Boersma, Eric; Bax, Jeroen J.; Feringa, Harm H.H.; Schouten, Olaf; van Sambeek, Marc r.H.M.; Poldermans, Don.

In: American journal of cardiology, Vol. 97, No. 10, 2006, p. 1423-1426.

Research output: Contribution to journalArticleAcademic

TY - JOUR

T1 - Influence of Cardiac Risk Factors and Medication on Length of Hospitalization in Patients Undergoing Major Vascular Surgery

AU - van de Pol, Marleen A.

AU - van Houdenhoven, Mark

AU - Hans, Elias W.

AU - Boersma, Eric

AU - Bax, Jeroen J.

AU - Feringa, Harm H.H.

AU - Schouten, Olaf

AU - van Sambeek, Marc r.H.M.

AU - Poldermans, Don

PY - 2006

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N2 - Major vascular surgery is associated with a long in-hospital length of stay (LOS). Cardiac risk factors identify patients with an increased risk. Recent studies have associated statin, aspirin, and β-blocker therapies with improved postoperative outcome. However, the effect of all these factors on LOS has not been defined. Our aims were to determine the effect of cardiac risk factors and (preventive) statin, aspirin, and β-blocker therapy on LOS and to deduce from these factors a model that predicts LOS. In total, 2,374 patients from 1990 to 2004 were enrolled. Mean LOS was 18 ± 9 days. Cardiac risk factors that were significantly associated with LOS in the multivariable analysis were age, previous heart failure, hypertension, diabetes mellitus, renal failure, and chronic obstructive pulmonary disease. Statin and aspirin use was associated with a shorter LOS. Beta blockers shortened LOS only in patients with underlying coronary artery disease. Together, these factors explained 14.1% of the variance in LOS. In conclusion, in-hospital LOS in patients who undergo major vascular surgery can be predicted more accurately by clinical cardiac risk factors. A significant decrease in in-hospital LOS was achieved with statin, aspirin, and β-blocker therapies.

AB - Major vascular surgery is associated with a long in-hospital length of stay (LOS). Cardiac risk factors identify patients with an increased risk. Recent studies have associated statin, aspirin, and β-blocker therapies with improved postoperative outcome. However, the effect of all these factors on LOS has not been defined. Our aims were to determine the effect of cardiac risk factors and (preventive) statin, aspirin, and β-blocker therapy on LOS and to deduce from these factors a model that predicts LOS. In total, 2,374 patients from 1990 to 2004 were enrolled. Mean LOS was 18 ± 9 days. Cardiac risk factors that were significantly associated with LOS in the multivariable analysis were age, previous heart failure, hypertension, diabetes mellitus, renal failure, and chronic obstructive pulmonary disease. Statin and aspirin use was associated with a shorter LOS. Beta blockers shortened LOS only in patients with underlying coronary artery disease. Together, these factors explained 14.1% of the variance in LOS. In conclusion, in-hospital LOS in patients who undergo major vascular surgery can be predicted more accurately by clinical cardiac risk factors. A significant decrease in in-hospital LOS was achieved with statin, aspirin, and β-blocker therapies.

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EP - 1426

JO - American journal of cardiology

JF - American journal of cardiology

SN - 0002-9149

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ER -