Influence of prostatic blood flow on laser prostatectomy

Christiaan F.P. Van Swol, Rudolf M. Verdaasdonk, Jaap Mooibroek, Tom A. Boon

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

3 Citations (Scopus)
20 Downloads (Pure)


Normally, a laser prostatectomy to treat Benign Prostatic Hyperplasia (BPH) is performed using a fixed dosimetry. Differences in, e.g., blood flow, optical properties and geometry, are not taken into account, although most of these differences may be distinguished when performing a cystoscopy, e.g., the color of the prostate. These characteristics show their influence in the final tissue effect. We developed a model to predict the permanent damage to the tissue. A Monte Carlo simulation program was used to calculate the light distribution in the prostate due to Nd:YAG laser light irradiation. Consequently, using the absorbed energy as a heat source, the thermal distribution in the tissue was computed using the method of finite differences. This numerical model was combined with a rate process damage model (Henriques equation) to make it possible to predict the extent of laser induced permanent damage (denaturation). The model is dynamic in time, which enabled us to observe the evolution of the damage process. In this flexible model blood vessels were incorporated. The blood vessels showed to have major influence on the temperature distribution and on the created damage. The vessels act like a heat sink, which clamps the temperature and shields the heat to penetrate deep into the tissue.

Original languageEnglish
Title of host publicationLasers in Urology
Number of pages6
Publication statusPublished - 2 May 1994
Externally publishedYes
EventLasers in Urology 1994 - Los Angeles, United States
Duration: 23 Jan 199429 Jan 1994

Publication series

NameProceedings of SPIE - the international society for optical engineering
ISSN (Print)0277-786X


ConferenceLasers in Urology 1994
Abbreviated titleOE/LASE '94
Country/TerritoryUnited States
CityLos Angeles


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