Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation

L. Fresiello; C. De Lazzari; M. G. Trivella; A. Di Molfetta; G. Ferrari

Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation

L. Fresiello
, C. De Lazzari^*
, M. G. Trivella
, A. Di Molfetta
, G. Ferrari

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

3 Citations (Scopus)

Abstract

Severe cardiovascular diseases can be treated using left ventricular assist devices (LVAD). One of the possible LVADs is the Pulsatile Catheter (PUCA) pump that consists of a hydraulically or pneumatically driven membrane pump connected to a valved catheter. In this work a numerical model of the cardiocirculatory system and of the PUCA have been developed in order to study their interaction. In the numerical simulator a pathological condition of the left ventricle has been reproduced and successively the effects of the PUCA on the haemodynamic variables applied were studied. Different functioning modes were tested by changing the ratio between the pump frequency and the heart beat rate (HR) as 1:1, 1:2 or 1:3 and by introducing a delay time between the cardiac and the PUCA cycle. The performance of the pump was evaluated in terms of cardiac output, PUCA and coronary flows and it was studied for different HR values. Results show a good resemblance between the model and literature data and indicate that different synchronization and timing can influence the functioning of the pump. In particular, the frequency ratio and the time delay of the pump cycle can contribute to optimize the performance of the PUCA.

Original language	English
Title of host publication	Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Pages	1-5
Number of pages	5
Publication status	Published - 2010
Externally published	Yes
Event	7th IASTED International Conference on Biomedical Engineering, BioMED 2010 - Innsbruck, Austria Duration: 17 Feb 2010 → 19 Feb 2010 Conference number: 7

Publication series

Name	Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Volume	1

Conference

Conference	7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Abbreviated title	BIOMED 2010
Country/Territory	Austria
City	Innsbruck
Period	17/02/10 → 19/02/10

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cardiovascular system
Haemodynamics
Modelling
Simulation
Ventricular assist device

Cite this

Fresiello, L., De Lazzari, C., Trivella, M. G., Di Molfetta, A., & Ferrari, G. (2010). Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation. In Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010 (pp. 1-5). (Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010; Vol. 1).

@inproceedings{4c0cb6a34aa34f3f8de5b8ce6f6e47b3,

title = "Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation",

abstract = "Severe cardiovascular diseases can be treated using left ventricular assist devices (LVAD). One of the possible LVADs is the Pulsatile Catheter (PUCA) pump that consists of a hydraulically or pneumatically driven membrane pump connected to a valved catheter. In this work a numerical model of the cardiocirculatory system and of the PUCA have been developed in order to study their interaction. In the numerical simulator a pathological condition of the left ventricle has been reproduced and successively the effects of the PUCA on the haemodynamic variables applied were studied. Different functioning modes were tested by changing the ratio between the pump frequency and the heart beat rate (HR) as 1:1, 1:2 or 1:3 and by introducing a delay time between the cardiac and the PUCA cycle. The performance of the pump was evaluated in terms of cardiac output, PUCA and coronary flows and it was studied for different HR values. Results show a good resemblance between the model and literature data and indicate that different synchronization and timing can influence the functioning of the pump. In particular, the frequency ratio and the time delay of the pump cycle can contribute to optimize the performance of the PUCA.",

keywords = "Cardiovascular system, Haemodynamics, Modelling, Simulation, Ventricular assist device",

author = "L. Fresiello and \{De Lazzari\}, C. and Trivella, \{M. G.\} and \{Di Molfetta\}, A. and G. Ferrari",

year = "2010",

language = "English",

isbn = "9780889868250",

series = "Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010",

pages = "1--5",

booktitle = "Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010",

note = "7th IASTED International Conference on Biomedical Engineering, BioMED 2010, BIOMED 2010 ; Conference date: 17-02-2010 Through 19-02-2010",

}

Fresiello, L, De Lazzari, C, Trivella, MG, Di Molfetta, A & Ferrari, G 2010, Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation. in Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010. Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010, vol. 1, pp. 1-5, 7th IASTED International Conference on Biomedical Engineering, BioMED 2010, Innsbruck, Austria, 17/02/10.

Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation. / Fresiello, L.; De Lazzari, C.; Trivella, M. G. et al.
Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010. 2010. p. 1-5 (Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Influence of pulsatile catheter pump synchronization on haemodynamic variables

T2 - 7th IASTED International Conference on Biomedical Engineering, BioMED 2010

AU - Fresiello, L.

AU - De Lazzari, C.

AU - Trivella, M. G.

AU - Di Molfetta, A.

AU - Ferrari, G.

N1 - Conference code: 7

PY - 2010

Y1 - 2010

N2 - Severe cardiovascular diseases can be treated using left ventricular assist devices (LVAD). One of the possible LVADs is the Pulsatile Catheter (PUCA) pump that consists of a hydraulically or pneumatically driven membrane pump connected to a valved catheter. In this work a numerical model of the cardiocirculatory system and of the PUCA have been developed in order to study their interaction. In the numerical simulator a pathological condition of the left ventricle has been reproduced and successively the effects of the PUCA on the haemodynamic variables applied were studied. Different functioning modes were tested by changing the ratio between the pump frequency and the heart beat rate (HR) as 1:1, 1:2 or 1:3 and by introducing a delay time between the cardiac and the PUCA cycle. The performance of the pump was evaluated in terms of cardiac output, PUCA and coronary flows and it was studied for different HR values. Results show a good resemblance between the model and literature data and indicate that different synchronization and timing can influence the functioning of the pump. In particular, the frequency ratio and the time delay of the pump cycle can contribute to optimize the performance of the PUCA.

AB - Severe cardiovascular diseases can be treated using left ventricular assist devices (LVAD). One of the possible LVADs is the Pulsatile Catheter (PUCA) pump that consists of a hydraulically or pneumatically driven membrane pump connected to a valved catheter. In this work a numerical model of the cardiocirculatory system and of the PUCA have been developed in order to study their interaction. In the numerical simulator a pathological condition of the left ventricle has been reproduced and successively the effects of the PUCA on the haemodynamic variables applied were studied. Different functioning modes were tested by changing the ratio between the pump frequency and the heart beat rate (HR) as 1:1, 1:2 or 1:3 and by introducing a delay time between the cardiac and the PUCA cycle. The performance of the pump was evaluated in terms of cardiac output, PUCA and coronary flows and it was studied for different HR values. Results show a good resemblance between the model and literature data and indicate that different synchronization and timing can influence the functioning of the pump. In particular, the frequency ratio and the time delay of the pump cycle can contribute to optimize the performance of the PUCA.

KW - Cardiovascular system

KW - Haemodynamics

KW - Modelling

KW - Simulation

KW - Ventricular assist device

UR - https://www.scopus.com/pages/publications/79953816878

M3 - Conference contribution

AN - SCOPUS:79953816878

SN - 9780889868250

T3 - Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010

SP - 1

EP - 5

BT - Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010

Y2 - 17 February 2010 through 19 February 2010

ER -

Fresiello L, De Lazzari C, Trivella MG, Di Molfetta A, Ferrari G. Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation. In Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010. 2010. p. 1-5. (Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010).

Influence of pulsatile catheter pump synchronization on haemodynamic variables: Numerical simulation

Abstract

Publication series

Conference

UN SDGs

Keywords

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