Initial experiences in the photoacoustic detection of melanoma metastases in resected lymph nodes

Diederik Grootendorst, J. Jose, P.K.N. van der Jagt, P. van der Jagt, W. van der Weg, K. Nagel, N.A. Nagel, M. Wouters, H. van Boven, Ton van Leeuwen, Wiendelt Steenbergen, Theo J.M. Ruers, Srirang Manohar

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

2 Citations (Scopus)

Abstract

Accurate lymph node analysis is essential to determine the prognosis and treatment of patients suffering from melanoma. The initial results of a tomographic photoacoustic modality to detect melanoma metastases in resected lymph nodes are presented based on phantom models and a human lymph node. The results show melanoma metastases detection is feasible and the setup is capable of distinguishing absorbing structures down to 1 mm. In addition, the use of longer laser wavelengths could result in an image containing a higher contrast ratio. Future research shall be focused on using the melanin characteristics to improve contrast and detection possibilities.
Original languageEnglish
Title of host publicationPhotons Plus Ultrasound: Imaging and Sensing 2011
EditorsAlexander A. Oraevsky, Lihong Wang
PublisherSPIE
Number of pages7
ISBN (Print)9780819484369
DOIs
Publication statusPublished - 10 Feb 2011
EventPhotons Plus Ultrasound: Imaging and Sensing 2011 - San Francisco, CA, USA
Duration: 17 Feb 201117 Feb 2011

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume7899
ISSN (Print)0277-786X

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2011
Period17/02/1117/02/11
OtherFebruary 17, 2011

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