Abstract
We report a new integrated Lab-on-a-Chip (LOC) and surface plasmon resonance imaging (iSPR) system that uses
electrokinetic (EK) sample transport simultaneously into 10 individual microchannels and 100 sensing locations, where
all sensing locations can be measured simultaneously and kinetics and affinity parameters extracted from all the
interactant pairs. This new chip can be used for high-throughput drug screening applications and the simultaneous
extraction of kinetics and affinity parameters from interactant-protein complex formation.
| Original language | English |
|---|---|
| Title of host publication | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 |
| Editors | Sabeth Verpoorte, Helen Andersson-Svahn, Jenny Emnéus, Nicole Pamme |
| Place of Publication | San Diego |
| Publisher | The Chemical and Biological Microsystems Society |
| Pages | 581-583 |
| Number of pages | 3 |
| ISBN (Electronic) | 978-0-9798064-3-8 |
| ISBN (Print) | 978-1-6183906-2-2 |
| Publication status | Published - 3 Oct 2010 |
| Event | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14 |
Publication series
| Name | International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings] |
|---|---|
| Publisher | The Chemical and Biological Microsystems Society |
| Volume | 2010 |
| ISSN (Print) | 1556-5904 |
Conference
| Conference | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 |
|---|---|
| Abbreviated title | MicroTAS 2010 |
| Country/Territory | Netherlands |
| City | Groningen |
| Period | 3/10/10 → 7/10/10 |
Keywords
- Lab-on-a-chip
- Biosensor
- Surface plasmon resonance imaging
- Drug screening
- Electrokinetics