Abstract
| Original language | English |
|---|---|
| Title of host publication | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 |
| Editors | Sabeth Verpoorte, Helen Andersson-Svahn, Jenny Emnéus, Nicole Pamme |
| Place of Publication | San Diego |
| Publisher | Chemical and Biological Micro Systems Society |
| Pages | 581-583 |
| Number of pages | 3 |
| ISBN (Electronic) | 978-0-9798064-3-8 |
| ISBN (Print) | 978-1-6183906-2-2 |
| Publication status | Published - 3 Oct 2010 |
| Event | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010 - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14 |
Publication series
| Name | International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings] |
|---|---|
| Publisher | The Chemical and Biological Microsystems Society |
| Volume | 2010 |
| ISSN (Print) | 1556-5904 |
Conference
| Conference | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010 |
|---|---|
| Abbreviated title | MicroTAS |
| Country | Netherlands |
| City | Groningen |
| Period | 3/10/10 → 7/10/10 |
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Keywords
- Lab-on-a-chip
- Biosensor
- Surface plasmon resonance imaging
- Drug screening
- Electrokinetics
Cite this
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Integrated electrokinetic Lab-on-a-chip based biosensor- a tool for drug screening applications. / Krishnamoorthy, G.; Carlen, E.T.; Schasfoort, R.B.M.; van den Berg, A.
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010. ed. / Sabeth Verpoorte; Helen Andersson-Svahn; Jenny Emnéus; Nicole Pamme. San Diego : Chemical and Biological Micro Systems Society, 2010. p. 581-583 (International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]; Vol. 2010).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
TY - GEN
T1 - Integrated electrokinetic Lab-on-a-chip based biosensor- a tool for drug screening applications
AU - Krishnamoorthy, G.
AU - Carlen, E.T.
AU - Schasfoort, R.B.M.
AU - van den Berg, A.
PY - 2010/10/3
Y1 - 2010/10/3
N2 - We report a new integrated Lab-on-a-Chip (LOC) and surface plasmon resonance imaging (iSPR) system that uses electrokinetic (EK) sample transport simultaneously into 10 individual microchannels and 100 sensing locations, where all sensing locations can be measured simultaneously and kinetics and affinity parameters extracted from all the interactant pairs. This new chip can be used for high-throughput drug screening applications and the simultaneous extraction of kinetics and affinity parameters from interactant-protein complex formation.
AB - We report a new integrated Lab-on-a-Chip (LOC) and surface plasmon resonance imaging (iSPR) system that uses electrokinetic (EK) sample transport simultaneously into 10 individual microchannels and 100 sensing locations, where all sensing locations can be measured simultaneously and kinetics and affinity parameters extracted from all the interactant pairs. This new chip can be used for high-throughput drug screening applications and the simultaneous extraction of kinetics and affinity parameters from interactant-protein complex formation.
KW - Lab-on-a-chip
KW - Biosensor
KW - Surface plasmon resonance imaging
KW - Drug screening
KW - Electrokinetics
M3 - Conference contribution
SN - 978-1-6183906-2-2
T3 - International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]
SP - 581
EP - 583
BT - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010
A2 - Verpoorte, Sabeth
A2 - Andersson-Svahn, Helen
A2 - Emnéus, Jenny
A2 - Pamme, Nicole
PB - Chemical and Biological Micro Systems Society
CY - San Diego
ER -