Integrated optoelectronic probe including a vertical cavity surface emitting laser for laser Doppler perfusion monitoring

Alexander Serov, Janharm Nieland, Sjoerd Oosterbaan, Frits F.M. de Mul, Herma van Kranenburg, Herman H.P.Th. Bekman, Wiendelt Steenbergen

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Abstract

An integrated optoelectronic probe with small dimensions, for direct-contact laser Doppler blood flow monitoring has been realized. A vertical cavity surface emitting laser (VCSEL), and a chip with photodetectors and all necessary electronics are integrated in a miniature probe head connected to a laptop computer. The computer sound processor is utilized for acquisition and digital signal processing of the incoming Doppler signal. In this paper, the design of the laser Doppler perfusion monitor is described and its performance is evaluated. We demonstrate our perfusion monitor to be less sensitive to subject motion than a commercial fiber-optic device. For medium and high perfusion levels, the performance of our integrated probe is comparable to the fiber-optic flowmeter containing a normal edge-emitting laser diode. For very low perfusion levels, the signal-to-noise ratio of the fiber-optic device is higher. This difference can mainly be attributed to the shorter coherence length of the VCSEL compared with the edge-emitting laser diode.
Original languageEnglish
Pages (from-to)2067-2074
Number of pages8
JournalIEEE transactions on biomedical engineering
Volume53
Issue number10
DOIs
Publication statusPublished - 2006

Fingerprint

Integrated optoelectronics
Surface emitting lasers
Fiber optics
Semiconductor lasers
Lasers
Monitoring
Laptop computers
Flowmeters
Photodetectors
Digital signal processing
Signal to noise ratio
Blood
Electronic equipment
Acoustic waves

Keywords

  • Blood flow measurement
  • Doppler effect
  • Optoelectronic devices
  • Semiconductor laser

Cite this

Serov, Alexander ; Nieland, Janharm ; Oosterbaan, Sjoerd ; de Mul, Frits F.M. ; van Kranenburg, Herma ; Bekman, Herman H.P.Th. ; Steenbergen, Wiendelt. / Integrated optoelectronic probe including a vertical cavity surface emitting laser for laser Doppler perfusion monitoring. In: IEEE transactions on biomedical engineering. 2006 ; Vol. 53, No. 10. pp. 2067-2074.
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abstract = "An integrated optoelectronic probe with small dimensions, for direct-contact laser Doppler blood flow monitoring has been realized. A vertical cavity surface emitting laser (VCSEL), and a chip with photodetectors and all necessary electronics are integrated in a miniature probe head connected to a laptop computer. The computer sound processor is utilized for acquisition and digital signal processing of the incoming Doppler signal. In this paper, the design of the laser Doppler perfusion monitor is described and its performance is evaluated. We demonstrate our perfusion monitor to be less sensitive to subject motion than a commercial fiber-optic device. For medium and high perfusion levels, the performance of our integrated probe is comparable to the fiber-optic flowmeter containing a normal edge-emitting laser diode. For very low perfusion levels, the signal-to-noise ratio of the fiber-optic device is higher. This difference can mainly be attributed to the shorter coherence length of the VCSEL compared with the edge-emitting laser diode.",
keywords = "Blood flow measurement, Doppler effect, Optoelectronic devices, Semiconductor laser",
author = "Alexander Serov and Janharm Nieland and Sjoerd Oosterbaan and {de Mul}, {Frits F.M.} and {van Kranenburg}, Herma and Bekman, {Herman H.P.Th.} and Wiendelt Steenbergen",
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Integrated optoelectronic probe including a vertical cavity surface emitting laser for laser Doppler perfusion monitoring. / Serov, Alexander; Nieland, Janharm; Oosterbaan, Sjoerd; de Mul, Frits F.M.; van Kranenburg, Herma; Bekman, Herman H.P.Th.; Steenbergen, Wiendelt.

In: IEEE transactions on biomedical engineering, Vol. 53, No. 10, 2006, p. 2067-2074.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Nieland, Janharm

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AB - An integrated optoelectronic probe with small dimensions, for direct-contact laser Doppler blood flow monitoring has been realized. A vertical cavity surface emitting laser (VCSEL), and a chip with photodetectors and all necessary electronics are integrated in a miniature probe head connected to a laptop computer. The computer sound processor is utilized for acquisition and digital signal processing of the incoming Doppler signal. In this paper, the design of the laser Doppler perfusion monitor is described and its performance is evaluated. We demonstrate our perfusion monitor to be less sensitive to subject motion than a commercial fiber-optic device. For medium and high perfusion levels, the performance of our integrated probe is comparable to the fiber-optic flowmeter containing a normal edge-emitting laser diode. For very low perfusion levels, the signal-to-noise ratio of the fiber-optic device is higher. This difference can mainly be attributed to the shorter coherence length of the VCSEL compared with the edge-emitting laser diode.

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