Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring

Alexander Serov; Sjoerd  L.T. Oosterbaan; Janharm Nieland; H. van Kranenburg; F.F.M. de Mul; Wiendelt Steenbergen

doi:10.1117/12.427929

Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring

Alexander Serov, Sjoerd L.T. Oosterbaan, Janharm Nieland, H. van Kranenburg, F.F.M. de Mul, Wiendelt Steenbergen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

1 Citation (Scopus)

Abstract

An integrated probe has been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device includes a VCSEL for illumination, and a chip containing photodetectors, analog amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform, which also includes an integrated temperature sensor. A Peltier element may be included for temperature stabilization, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the multidetector chip and the probe design are presented.

Original language	English
Title of host publication	SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III
Publisher	SPIE
Pages	119-127
Number of pages	9
ISBN (Print)	0-8194-3932-0
DOIs	https://doi.org/10.1117/12.427929
Publication status	Published - 21 Jan 2001
Event	Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III - San Jose, CA, USA Duration: 21 Jan 2001 → 22 Jan 2001

Publication series

Name	Proceedings of SPIE, Progress in biomedical optics and imaging
Publisher	SPIE
Volume	4254
ISSN (Print)	1605-7422

Conference

Conference	Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III
Period	21/01/01 → 22/01/01
Other	January 21-22, 2001

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10.1117/12.427929

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Serov, A., Oosterbaan, S. L. T., Nieland, J., van Kranenburg, H., de Mul, F. F. M., & Steenbergen, W. (2001). Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring. In SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III (pp. 119-127). (Proceedings of SPIE, Progress in biomedical optics and imaging; Vol. 4254). SPIE. https://doi.org/10.1117/12.427929

Serov, Alexander ; Oosterbaan, Sjoerd L.T. ; Nieland, Janharm ; van Kranenburg, H. ; de Mul, F.F.M. ; Steenbergen, Wiendelt. / Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring. SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III. SPIE, 2001. pp. 119-127 (Proceedings of SPIE, Progress in biomedical optics and imaging).

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title = "Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring",

abstract = "An integrated probe has been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device includes a VCSEL for illumination, and a chip containing photodetectors, analog amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform, which also includes an integrated temperature sensor. A Peltier element may be included for temperature stabilization, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the multidetector chip and the probe design are presented.",

author = "Alexander Serov and Oosterbaan, {Sjoerd L.T.} and Janharm Nieland and {van Kranenburg}, H. and {de Mul}, F.F.M. and Wiendelt Steenbergen",

year = "2001",

month = jan,

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doi = "10.1117/12.427929",

language = "English",

isbn = "0-8194-3932-0",

series = "Proceedings of SPIE, Progress in biomedical optics and imaging",

publisher = "SPIE",

pages = "119--127",

booktitle = "SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III",

address = "United States",

note = "Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III ; Conference date: 21-01-2001 Through 22-01-2001",

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Serov, A, Oosterbaan, SLT, Nieland, J, van Kranenburg, H, de Mul, FFM & Steenbergen, W 2001, Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring. in SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III. Proceedings of SPIE, Progress in biomedical optics and imaging, vol. 4254, SPIE, pp. 119-127, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III, 21/01/01. https://doi.org/10.1117/12.427929

Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring. / Serov, Alexander; Oosterbaan, Sjoerd L.T.; Nieland, Janharm; van Kranenburg, H.; de Mul, F.F.M.; Steenbergen, Wiendelt.

SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III. SPIE, 2001. p. 119-127 (Proceedings of SPIE, Progress in biomedical optics and imaging; Vol. 4254).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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N2 - An integrated probe has been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device includes a VCSEL for illumination, and a chip containing photodetectors, analog amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform, which also includes an integrated temperature sensor. A Peltier element may be included for temperature stabilization, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the multidetector chip and the probe design are presented.

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Serov A, Oosterbaan SLT, Nieland J, van Kranenburg H, de Mul FFM, Steenbergen W. Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring. In SPIE Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III. SPIE. 2001. p. 119-127. (Proceedings of SPIE, Progress in biomedical optics and imaging). https://doi.org/10.1117/12.427929

Integrated probes containing a VCSEL and a multidetector chip, for laser Doppler tissue perfusion monitoring

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