Interaction of Anionic Bulk Nanobubbles with Cationic Liposomes: Evidence for Reentrant Condensation

Minmin Zhang, Serge G. Lemay*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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We investigated the interaction of bulk nanobubbles with cationic liposomes composed of 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine and anionic liposomes assembled from 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol). We employed dynamic light scattering and fluorescence microscopy to investigate both the hydrodynamic and electrophoretic properties of the nanobubble/liposome complexes. These optical techniques permit direct visualization of structural changes as a function of the bubble/liposome ratio. We observed reentrant condensation with cationic liposomes and gas nucleation with anionic liposomes. This is the first report of charge inversion and reentrant condensation of cationic liposomes induced by bulk nanobubbles.

Original languageEnglish
Pages (from-to)4146-4151
Number of pages6
Issue number11
Publication statusPublished - 19 Mar 2019

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