This chapter provides a global overview of the topic treated in this book. In particular, we shall firstly contextualize the work in the wide panorama of aerial robotics, and more precisely, of aerial physical interaction. Afterword, we will focus our attention to the topic of this work, i.e., tethered aerial vehicles. We shall cover the scientific and practical motivations that brought us analyzing these kind of systems, listing the several objectives and challenges at which we aim in this work. We finally provide a reader’s guide describing in a detailed way the organization and content of the book.