Investigating the potential of low concentrations of iron-oxide contrast agents at low magnetic field strengths for the purpose of MR guided interventions

Research output: Contribution to conferenceAbstract

7 Downloads (Pure)

Abstract

Iron-oxide contrast agents might prove valuable in endovascular interventions at low-field MRI because their relaxivities are more favorable at lower field strengths, but still maintaining and generating positive contrast. Differences between a range concentrations of a gadolinium-based and a super paramagnetic iron-oxide (SPIO) contrast agent were compared both in simulations and experimentally on 0.25T using three different MR sequences. Optimal contrast for all sequences was found around 0.15mM for the SPIO agent and for concentrations higher than 7.0mM for the gadolinium agent. The use of low concentration SPIOs therefore is more beneficial for imaging at low magnetic field strengths than gadolinium-based contrast agents.
Original languageEnglish
Publication statusPublished - 2018
Event10th Annual ISMRM Benelux Chapter Meeting 2018 - Antwerp Zoo, Belgium, Antwerpen, Belgium
Duration: 26 Jan 201826 Jan 2018
Conference number: 10
http://www.ismrm-benelux.org/

Conference

Conference10th Annual ISMRM Benelux Chapter Meeting 2018
CountryBelgium
CityAntwerpen
Period26/01/1826/01/18
Internet address

Fingerprint

iron oxides
low concentrations
field strength
gadolinium
magnetic fields
simulation

Cite this

@conference{34c27c8543ef4854afcb29544639e01d,
title = "Investigating the potential of low concentrations of iron-oxide contrast agents at low magnetic field strengths for the purpose of MR guided interventions",
abstract = "Iron-oxide contrast agents might prove valuable in endovascular interventions at low-field MRI because their relaxivities are more favorable at lower field strengths, but still maintaining and generating positive contrast. Differences between a range concentrations of a gadolinium-based and a super paramagnetic iron-oxide (SPIO) contrast agent were compared both in simulations and experimentally on 0.25T using three different MR sequences. Optimal contrast for all sequences was found around 0.15mM for the SPIO agent and for concentrations higher than 7.0mM for the gadolinium agent. The use of low concentration SPIOs therefore is more beneficial for imaging at low magnetic field strengths than gadolinium-based contrast agents.",
author = "{van Zandwijk}, {Jordy Kristian} and Simonis, {Franciscus Frederikus Jacobus} and Elfi Hofmeijer and Geelkerken, {Robert Herman} and {ten Haken}, Bernard",
year = "2018",
language = "English",
note = "10th Annual ISMRM Benelux Chapter Meeting 2018 ; Conference date: 26-01-2018 Through 26-01-2018",
url = "http://www.ismrm-benelux.org/",

}

TY - CONF

T1 - Investigating the potential of low concentrations of iron-oxide contrast agents at low magnetic field strengths for the purpose of MR guided interventions

AU - van Zandwijk, Jordy Kristian

AU - Simonis, Franciscus Frederikus Jacobus

AU - Hofmeijer, Elfi

AU - Geelkerken, Robert Herman

AU - ten Haken, Bernard

PY - 2018

Y1 - 2018

N2 - Iron-oxide contrast agents might prove valuable in endovascular interventions at low-field MRI because their relaxivities are more favorable at lower field strengths, but still maintaining and generating positive contrast. Differences between a range concentrations of a gadolinium-based and a super paramagnetic iron-oxide (SPIO) contrast agent were compared both in simulations and experimentally on 0.25T using three different MR sequences. Optimal contrast for all sequences was found around 0.15mM for the SPIO agent and for concentrations higher than 7.0mM for the gadolinium agent. The use of low concentration SPIOs therefore is more beneficial for imaging at low magnetic field strengths than gadolinium-based contrast agents.

AB - Iron-oxide contrast agents might prove valuable in endovascular interventions at low-field MRI because their relaxivities are more favorable at lower field strengths, but still maintaining and generating positive contrast. Differences between a range concentrations of a gadolinium-based and a super paramagnetic iron-oxide (SPIO) contrast agent were compared both in simulations and experimentally on 0.25T using three different MR sequences. Optimal contrast for all sequences was found around 0.15mM for the SPIO agent and for concentrations higher than 7.0mM for the gadolinium agent. The use of low concentration SPIOs therefore is more beneficial for imaging at low magnetic field strengths than gadolinium-based contrast agents.

M3 - Abstract

ER -