Investigating the potential of low concentrations of iron-oxide contrast agents at low magnetic field strengths for the purpose of MR guided interventions

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Abstract

Iron-oxide contrast agents might prove valuable in endovascular interventions at low-field MRI because their relaxivities are more favorable at lower field strengths, but still maintaining and generating positive contrast. Differences between a range concentrations of a gadolinium-based and a super paramagnetic iron-oxide (SPIO) contrast agent were compared both in simulations and experimentally on 0.25T using three different MR sequences. Optimal contrast for all sequences was found around 0.15mM for the SPIO agent and for concentrations higher than 7.0mM for the gadolinium agent. The use of low concentration SPIOs therefore is more beneficial for imaging at low magnetic field strengths than gadolinium-based contrast agents.
Original languageEnglish
Publication statusPublished - 2018
Event10th Annual ISMRM Benelux Chapter Meeting 2018 - Antwerp Zoo, Belgium, Antwerpen, Belgium
Duration: 26 Jan 201826 Jan 2018
Conference number: 10
http://www.ismrm-benelux.org/

Conference

Conference10th Annual ISMRM Benelux Chapter Meeting 2018
CountryBelgium
CityAntwerpen
Period26/01/1826/01/18
Internet address

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