Label-free Enzyme Sensing with Grated Silicon Photonic Wire

L.J. Kauppinen, Mindert Dijkstra, Hugo Hoekstra, R.M. de Ridder

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    Abstract

    We have investigated the label-free biosensing properties of grated silicon photonic wire (GSPW) waveguides with cross-sectional dimensions of 350 nm x 220 nm, fabricated using a 248-nm deep UV lithography process. The steep edges of the optical transmission spectrum of the GSPW enable detection of very small spectral shift, hence of small index changes. To obtain an antibody layer for the biosensing experiment, an immobilization process is required. We followed the standard immobilization process developed by Imenz B.V. The antibody immobilization process and the binding process of enzymes on an immobilized antibody layer have been monitored with the GSPW based sensor.
    Original languageUndefined
    Title of host publicationProceedings of the 2009 Annual Symposium of the IEEE Photonics Benelux Chapter
    EditorsStefano Beri, Philippe Tassin, Gordon Craggs, Xaveer Leijtens, Jan Dankaert
    PublisherVUBPress Brussels University Press
    Pages41-44
    Number of pages4
    ISBN (Print)978-90-5487-650-2
    Publication statusPublished - 5 Nov 2009
    Event14th Annual Symposium of the IEEE Photonics Benelux Chapter 2009 - Brussels, Belgium
    Duration: 5 Nov 20096 Nov 2009
    Conference number: 14

    Publication series

    Name
    PublisherVUBPress Brussels University Press

    Conference

    Conference14th Annual Symposium of the IEEE Photonics Benelux Chapter 2009
    CountryBelgium
    CityBrussels
    Period5/11/096/11/09

    Keywords

    • IR-69940
    • METIS-265791
    • Label-free sensing
    • EWI-17443
    • photonic wire
    • IOMS-SNS: SENSORS
    • IOMS-PCS: PHOTONIC CRYSTAL STRUCTURES
    • Silicon

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