Label-free Enzyme Sensing with Grated Silicon Photonic Wire

L.J. Kauppinen; Mindert Dijkstra; Hugo Hoekstra; R.M. de Ridder

Label-free Enzyme Sensing with Grated Silicon Photonic Wire

L.J. Kauppinen, Mindert Dijkstra, Hugo Hoekstra, R.M. de Ridder

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

We have investigated the label-free biosensing properties of grated silicon photonic wire (GSPW) waveguides with cross-sectional dimensions of 350 nm x 220 nm, fabricated using a 248-nm deep UV lithography process. The steep edges of the optical transmission spectrum of the GSPW enable detection of very small spectral shift, hence of small index changes. To obtain an antibody layer for the biosensing experiment, an immobilization process is required. We followed the standard immobilization process developed by Imenz B.V. The antibody immobilization process and the binding process of enzymes on an immobilized antibody layer have been monitored with the GSPW based sensor.

Original language	Undefined
Title of host publication	Proceedings of the 2009 Annual Symposium of the IEEE Photonics Benelux Chapter
Editors	Stefano Beri, Philippe Tassin, Gordon Craggs, Xaveer Leijtens, Jan Dankaert
Publisher	VUBPress Brussels University Press
Pages	41-44
Number of pages	4
ISBN (Print)	978-90-5487-650-2
Publication status	Published - 5 Nov 2009
Event	14th Annual Symposium of the IEEE Photonics Benelux Chapter 2009 - Brussels, Belgium Duration: 5 Nov 2009 → 6 Nov 2009 Conference number: 14

Publication series

Name
Publisher	VUBPress Brussels University Press

Conference

Conference	14th Annual Symposium of the IEEE Photonics Benelux Chapter 2009
Country/Territory	Belgium
City	Brussels
Period	5/11/09 → 6/11/09

Keywords

IR-69940
METIS-265791
Label-free sensing
EWI-17443
photonic wire
IOMS-SNS: SENSORS
IOMS-PCS: PHOTONIC CRYSTAL STRUCTURES
Silicon

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Cite this

Kauppinen, L. J., Dijkstra, M., Hoekstra, H., & de Ridder, R. M. (2009). Label-free Enzyme Sensing with Grated Silicon Photonic Wire. In S. Beri, P. Tassin, G. Craggs, X. Leijtens, & J. Dankaert (Eds.), Proceedings of the 2009 Annual Symposium of the IEEE Photonics Benelux Chapter (pp. 41-44). VUBPress Brussels University Press. http://eprints.eemcs.utwente.nl/secure2/17443/01/Label-free_Enzyme_Sensing_with_Grated_Silicon_Photonic_Wire.pdf

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title = "Label-free Enzyme Sensing with Grated Silicon Photonic Wire",

abstract = "We have investigated the label-free biosensing properties of grated silicon photonic wire (GSPW) waveguides with cross-sectional dimensions of 350 nm x 220 nm, fabricated using a 248-nm deep UV lithography process. The steep edges of the optical transmission spectrum of the GSPW enable detection of very small spectral shift, hence of small index changes. To obtain an antibody layer for the biosensing experiment, an immobilization process is required. We followed the standard immobilization process developed by Imenz B.V. The antibody immobilization process and the binding process of enzymes on an immobilized antibody layer have been monitored with the GSPW based sensor.",

keywords = "IR-69940, METIS-265791, Label-free sensing, EWI-17443, photonic wire, IOMS-SNS: SENSORS, IOMS-PCS: PHOTONIC CRYSTAL STRUCTURES, Silicon",

author = "L.J. Kauppinen and Mindert Dijkstra and Hugo Hoekstra and {de Ridder}, R.M.",

year = "2009",

month = nov,

day = "5",

language = "Undefined",

isbn = "978-90-5487-650-2",

publisher = "VUBPress Brussels University Press",

pages = "41--44",

editor = "Stefano Beri and Philippe Tassin and Gordon Craggs and Xaveer Leijtens and Jan Dankaert",

booktitle = "Proceedings of the 2009 Annual Symposium of the IEEE Photonics Benelux Chapter",

note = "14th Annual Symposium of the IEEE Photonics Benelux Chapter 2009 ; Conference date: 05-11-2009 Through 06-11-2009",

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Kauppinen, LJ, Dijkstra, M, Hoekstra, H & de Ridder, RM 2009, Label-free Enzyme Sensing with Grated Silicon Photonic Wire. in S Beri, P Tassin, G Craggs, X Leijtens & J Dankaert (eds), Proceedings of the 2009 Annual Symposium of the IEEE Photonics Benelux Chapter. VUBPress Brussels University Press, pp. 41-44, 14th Annual Symposium of the IEEE Photonics Benelux Chapter 2009, Brussels, Belgium, 5/11/09. <http://eprints.eemcs.utwente.nl/secure2/17443/01/Label-free_Enzyme_Sensing_with_Grated_Silicon_Photonic_Wire.pdf>

Label-free Enzyme Sensing with Grated Silicon Photonic Wire. / Kauppinen, L.J.; Dijkstra, Mindert; Hoekstra, Hugo et al.
Proceedings of the 2009 Annual Symposium of the IEEE Photonics Benelux Chapter. ed. / Stefano Beri; Philippe Tassin; Gordon Craggs; Xaveer Leijtens; Jan Dankaert. VUBPress Brussels University Press, 2009. p. 41-44.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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